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Clinical Trials/NCT04384328
NCT04384328
Terminated
Not Applicable

Evaluation of an Early Support Programme in Orthophony : the PAPEV-ortho Study

Centre Hospitalier Sud Francilien4 sites in 1 country76 target enrollmentNovember 27, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Language Development Disorders
Sponsor
Centre Hospitalier Sud Francilien
Enrollment
76
Locations
4
Primary Endpoint
Score in the Ages & Stages Questionnaires communication domain at 24 months of corrected age.
Status
Terminated
Last Updated
3 years ago

Overview

Brief Summary

Prospective, interventionnal with minimal risks and constraints, multicentric, non-randomized, open study, to measure the impact of an early support programme in speech and language therapy for vulnerable children (PAPEV-ortho), in children born very prematurely or very hypotrophically, on the incidence of language and communication deficits at the corrected age of 2 years.

Detailed Description

Prospective, interventionnal with minimal risks and constraints, multicentric, non-randomized, open study, to measure the impact of an early support programme in speech and language therapy for vulnerable children (PAPEV-ortho), in children born very prematurely or very hypotrophically, on the incidence of language and communication deficits at the corrected age of 2 years. Parents of eligible children are informed of the study either during the hospitalization of the neonatal newborn by a hospital physician, or during a consultation performed during the first 6 months by a pilot physician from the RPSOF-ASNR network, hospital or private practitioner. Parents who agree that the data collected about their child may be used in the study sign a written declaration of free and informed consent. The Early Support Programme in orthophony (PAPEV-ortho) is systematically proposed to families with possible access to a language therapist in the network. Early support in speech therapy lasts between 6 months and 24 months of corrected age. It includes 10 to 20 sessions depending on the child's needs. These sessions are conducted by a speech-language pathologist from the RPSOF-ASNR network, trained in the issues specific to the very premature child and the network's tools. The support focuses on: * the development of parental sensitivity and receptivity * the development of parental reactivity * optimization of communication sequences in routine acts and play * the development of the child's intentionality in play and routine acts * support for verbal and non-verbal oral communication The participation of the child and his or her parents in the study ends at the end of the consultations and evaluations carried out at 24 months of corrected age. Children within the group that followed the PAPEV-ortho program will be compared to children who did not benefit from this program.

Registry
clinicaltrials.gov
Start Date
November 27, 2019
End Date
December 31, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Premature birth \< 32 weeks of amenorrhea
  • or premature birth with intrauterine growth restriction (IUGR) \< P3
  • corrected age ≤ 6 months at the time of inclusion
  • affiliation to a social security system + mutual insurance

Exclusion Criteria

  • genetic pathology
  • ongoing developmental care: psychomotricity or speech therapy
  • neuromuscular pathology affecting oral and facial motor skills
  • severe oral disorders: feeding by gastric tube or gastrostomy
  • severe sensory, auditory or visual impairment
  • neither of the 2 French-speaking parents

Outcomes

Primary Outcomes

Score in the Ages & Stages Questionnaires communication domain at 24 months of corrected age.

Time Frame: at 24 months of corrected age

Percentage of children with a score of ≤ 45 in the communication domain of the Ages \& Stages Questionnaires questionnaire (from 0=worst to 60=best) at 24 months of corrected age

Secondary Outcomes

  • Score in the Ages & Stages Questionnaires communication domain at 12 and 18 months of corrected age.(at 12 and 18 months of corrected age.)
  • Failure rate of implementation of the early support program in speech-language pathology or early drop-out.(at 24 months of corrected age)
  • score at Inventaire Français du Développement Communicatif questionnaire at 12, 18 and 24 months of corrected age(at 12, 18 and 24 months of corrected age)
  • Score at Communication and Symbolic Behavior Scales questionnaire at 12 and 24 months of corrected age(at 12 and 24 months of corrected age)

Study Sites (4)

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