Clamp-crush Technique Versus Harmonic Scalpel in Living Donor Hepatectomy

Phase 2

Completed

• Conditions: Hepatic Transplantation
• Interventions: Device: Kelly clamp crush technique; Device: Harmonic scalpel

• Registration Number: NCT02853981
• Lead Sponsor: Mansoura University

Brief Summary

The purpose of this study is to determine whether clamp-crush technique for liver parenchymal transection is as safe as Harmonic scalpel device. outcomes will include: perioperative mortality, surgery-related complications, blood loss, amount of blood loss during hepatectomy, operating time, transection speed, markers of liver parenchymal injury and hospital stay.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-01
• Study First Submitted: 2016-03-11
• Study First Submitted QC: 2016-08-02
• Study First Posted: 2016-08-03
• Primary Completion: 2016-09
• Study Completion: 2016-09
• Status Verified: 2018-01
• Last Update Submitted: 2018-01-17
• Last Update Posted: 2018-01-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

• Liver right lobe donors

Exclusion Criteria

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
clamp-crush group	Kelly clamp crush technique	group of donors whom will undergo liver transection using Kelly clamp.
Harmonic scalpel group	Harmonic scalpel	group of donors whom will undergo liver transection using harmonic scalpel.

Primary Outcome Measures

Name	Time	Method
blood loss during hepatectomy	intraoperative	bleeding during transection phase will be calculated in mL. based on the blood in the sucker machine and the surgical towels

Secondary Outcome Measures

Name	Time	Method
liver pathology from the cut margin	intraoperative	the area of necrosis will be measured in millimeters by the pathologist
transection speed	intraoperative	the transection speed will be calculated in minutes based on the relation between the transecition time divided by the surface area of the raw area of the graft measured on the backtable.

Trial Locations

Locations (1)

Gastro-enterolgy surgical center, Mansoura University; 🇪🇬 Mansoura, Al-Dakahleia, Egypt