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Clinical Trials/NCT04422795
NCT04422795
Withdrawn
Phase 4

The Evaluation of External Thermomechanical Stimulation for Pain Reduction in Patients Undergoing Nail Injection

Weill Medical College of Cornell University1 site in 1 countryFebruary 2024

Overview

Phase
Phase 4
Intervention
External thermomechanical device delivering cold and vibration stimuli
Conditions
Nail Diseases
Sponsor
Weill Medical College of Cornell University
Locations
1
Primary Endpoint
The level of pain and change in pain between each time point will be assessed using the Wong-Baker FACES scale with use of thermomechanical device delivering stimuli, without delivering stimuli, and with use of ethyl chloride skin refrigerant spray.
Status
Withdrawn
Last Updated
3 years ago

Overview

Brief Summary

The purpose of this study is to assess the efficacy and safety of a thermomechanical device delivering vibration and cold stimuli in lowering pain during intramatricial nail injections

Registry
clinicaltrials.gov
Start Date
February 2024
End Date
July 2025
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Men and women aged 18 years or older
  • Must understand and voluntarily sign an informed consent form
  • All patients undergoing intramatricial nail injections at the Weill Cornell Medicine (WCM) Department of Dermatology
  • Willingness to participate in the study

Exclusion Criteria

  • Inability of the patient to provide written informed consent for any reason
  • Failure to have nail injection performed
  • Likely inability to comply with the study protocol or cooperate fully with the research team

Arms & Interventions

External thermomechanical device delivering stimuli

The thermomechanical device is placed on the digit proximally to the injection site with the ice wings frozen and the vibration mechanism switched on.

Intervention: External thermomechanical device delivering cold and vibration stimuli

External thermomechanical device without delivering stimuli

The thermomechanical device is placed on the digit proximally to the injection site with the ice wings at room temperature (unfrozen) and the vibration mechanism switched off.

Intervention: External thermomechanical device without delivering cold and vibration stimuli

Nail injection with ethyl chloride skin refrigerant spray

Ethyl chloride skin refrigerant spray is applied to the area of injection immediately before needle insertion

Intervention: Ethyl chloride skin refrigerant spray

Outcomes

Primary Outcomes

The level of pain and change in pain between each time point will be assessed using the Wong-Baker FACES scale with use of thermomechanical device delivering stimuli, without delivering stimuli, and with use of ethyl chloride skin refrigerant spray.

Time Frame: prior to treatment, immediately after the needle insertion, during infiltration and 5 seconds after needle extraction

Pain will be self-reported, using the Wong-Baker FACES (0-10, with 0 representing absence of pain and 10 unbearable pain). Participants will be questioned about their level of pain in their nail prior to treatment, immediately after the needle insertion, during infiltration, and 5 seconds after needle extraction

Secondary Outcomes

  • Number of participants with at least one adverse event(Patients will be followed for 3 days following their nail injection)

Study Sites (1)

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