Endoscopic drainage of presumed resectable perihilar cholangiocarcinoma using a novel design short fully covered self-expanding metal stent with retrieval string (CHORDA)
- Conditions
- (Potentially) resectable perihilar cholanhiocarcinoma
- Registration Number
- NL-OMON22954
- Lead Sponsor
- Amsterdam UMC
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 20
18 years or older.
- Capable of providing written and oral informed consent.
- Presumed perihilar cholangiocarcinoma.
- Biliary obstruction in the future liver remnant.
- Drainage naïve patients: total bilirubin >50 umol/L
- Patients with previous endobiliary drainage procedures: persistently rising total bilirubin >50 umol/L (i.e. no stent placed or insufficient draining stent) or persistent biliary dilatation in the future liver remnant on imaging (i.e. previous stent placed in contralateral side of the liver).
- Incompletely recovered from any side effects of previous biliary drainage procedures. Patients are required to be off antibiotic treatment for at least 5 days.
- Any contra-indication for major liver surgery (e.g. ECOG/WHO score 3 or higher).
- Technical contra-indications for endobiliary drainage (e.g. previous gastrojejunostomy).
- Refusal to provide informed consent.
- Requirement of multiple stents for adequate drainage of the future liver remnant (e.g. involvement of segmental bile ducts).
- In case it is not feasible to prevent blockage of one or more large segmental branches.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method