A novel biomarker of food addiction: an investigation in females to determine if plasma oxytocin concentrations are associated with food addiction and if oxytocin concentrations are changed in response to visual food cues.

Not Applicable

Completed

• Conditions: Food addiction; Diet and Nutrition - Obesity; Obesity

• Registration Number: ACTRN12619000351112
• Lead Sponsor: niversity of Newcastle

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2018-04-23
• Study Start: 2019-03-06
• Last Update Posted: 16 March 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 22

Inclusion Criteria

Females 18-85yrs, able to comprehend English, willing to attend the University of Newcastle for a one off occasion. Females with and without food addiction, from a previous study sample [Burrows et al, Differences in Dietary Preferences, Personality and Mental Health in Australian Adults with and without Food Addiction. Nutrients. 2017; 9(3). pii: E285. doi: 10.3390/nu9030285] which investigated food addiction and mental health, who agreed to be recontacted for future studies, will be invited to participate via email.

Exclusion Criteria

No existing health conditions or conditions which effect dietary intake (e.g. Coeliac; food allergies or intolerances), binge eating disorder, substance use disorder, current smokers, pregnant or lactating women, use of anti-depressant drugs or undergoing steroid treatment, cognitive impairment or mental health condition (e.g. bipolar disorder or psychosis) requiring ongoing psychiatric treatment.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Plasma concentrations of oxytocin[Baseline and immediately after each image paradigm]

Secondary Outcome Measures

Name	Time	Method
Plasma concentrations of ghrelin assessed by enzyme-linked immunoassay (ELISA) [Baseline and immediately after each image paradigm];Plasma concentrations of leptin assessed by ELISA <br>[Baseline and immediately after each image paradigm];Plasma concentrations of cholecystokinin assessed by ELISA <br>[Baseline and immediately after each image paradigm];Plasma concentrations of cortisol assessed by ELISA <br>[Baseline and immediately after each image paradigm]