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Which is Better Piezosurgery or LLLT in Accelerating Orthodontic Tooth Movement

Not Applicable
Completed
Conditions
Class II Malocclusion
Interventions
Procedure: Piezocision
Device: Low-level laser
Device: Conventional treatment
Registration Number
NCT05227859
Lead Sponsor
Damascus University
Brief Summary

Sixty patients need extraction-based treatment of the maxillary first premolars with subsequent retraction of the maxillary canines will be divided randomly into three groups: piezocision group, low-level laser therapy group, and control group. In each group, the canine retraction will be started after completion of the leveling and alignment phase via closed nickel-titanium coil springs applying 150 g of force per side. For anchorage, a soldered trans-palatal arch will be used.

Pre- and post distalization dental casts will be assessed to study the rate of canine retraction, as well as, canine rotation and anchorage loss over a follow-up period until a class I canine relationship is achieved.

Detailed Description

Before enrollment of each subject into the study, they will be examined completely to ensure their eligibility for this study. The operator will inform them about the aim of the study and ask them to provide written informed consent.

At the end of leveling and alignment stage, the upper first premolars will be extracted. The rectangular stainless steel archwires (0.019" × 0.025") will be inserted, then after one month, the canine retraction will be started.

Regarding the Piezocision, after anesthesia, three vertical incisions will be made (3-mm depth and 8-10 mm length) mesial and distal the upper canine as well as at an equal distance from the upper canine and 2nd premolar. The surgical procedures will be repeated after six weeks (only the mesial and distal canine incisions will be done) Regarding the low-level laser therapy (LLLT): GaALAs diode laser (wavelength: 810 nm and exposure time of 10 seconds\\point) will be applied around the upper canine in 10 sites from buccal and palatal. The middle of the extraction site will be also irradiated in 4 sites (2 buccally and 2 palatally). The LLLT will be applied 5 times in the first month of canine retraction, then every two weeks until class I canine relationship will be achieved.

The upper canine destalization will be done using NiTi springs. The force level will be controlled every 2 weeks. Retraction will be stopped when a class I canine relationship in both sides.

Dental casts will be used for the quantification of the anteroposterior movement of the upper canine and the first molars every 30 days until the class I canine relationship will be achieved.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
60
Inclusion Criteria
  1. Adult healthy patients, Male and female, Age range: 17-28 years.

  2. Class II Division 1 malocclusion :

    • Mild/moderate skeletal Class II (sagittal discrepancy angle ≤7)
    • Overjet ≤10
    • Normal or excessive facial height (Clinically and then cephalometrically assessed using these three angles: mandibular/cranial base angle, maxillary/mandibular plane angle, and facial axis angle)
    • Mild to moderate crowding ≤ 4
  3. Permanent occlusion.

  4. Existence of all the upper teeth (except third molars).

  5. Good oral and periodontal health:

    • Probing depth < 4 mm
    • No radiographic evidence of bone loss.
    • Gingival index ≤ 1
    • Plaque index ≤ 1
Exclusion Criteria
  1. Medical problems that affect tooth movement (corticosteroid, nonsteroidal anti-inflammatory drugs (NSAIDs), ...)

  2. Presence of primary teeth in the maxillary arch

  3. Missing permanent maxillary teeth (except third molars).

  4. Poor oral hygiene or Current periodontal disease:

    • Probing depth ≥ 4 mm
    • radiographic evidence of bone loss
    • Gingival index > 1
    • Plaque index > 1
  5. Patient had previous orthodontic treatment

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Piezocision therapyPiezocisionIn this group of patients, the canine will be retracted in association with piezocision.
Low-level laser therapyLow-level laserIn this group of patients, the canine will be retracted in association with LLLT.
Conventional treatmentConventional treatmentIn this group of patients, the canine will be retracted conventionally without any acceleration intervention.
Primary Outcome Measures
NameTimeMethod
Duration of upper canine retractionThe months required to complete the retraction procedure will be recorded. Completion of this procedure is expected to occur within four months in the experimental groups and seven months in the control group

Assessment will be performed by calculating the months required to achieve complete retraction of the upper canine retraction through clinical examination.

Rate of retractionTime Frame: The calculation of the rate of retraction will be done once the retraction procedures have finished. Completion of this procedure is expected to occur within 4 months in the experimental groups and 7 months in the control group.

Assessment will be performed on study models. The amount of distance being retracted in millimeters will be divided by the duration of retraction in weeks to give an estimation of the retraction rate.

Secondary Outcome Measures
NameTimeMethod
Change in canine' rotationT0: 1 day before the beginning of canine retraction; T1: after 1 month of retraction; T2: after 2 months of retraction; T3: after 3 months of retraction; and T4: at the end of retraction (expected to be within 4 months to 7 months)

The amount of the rotation of canine is going to be measured on study models taken at monthly intervals until the end of the retraction phase.

Change in Molars' positionsT0: 1 day before the beginning of canine retraction; T1: after 1 month of retraction; T2: after 2 months of retraction; T3: after 3 months; and T4: at the end of retraction (expected to be within 4 months to 7 months))

The amount of distance being traveled by the first molars is going to be measured on study models taken at monthly intervals until the end of the retraction phase.

Trial Locations

Locations (1)

Department of Orthodontics, University of Damascus Dental School

🇸🇾

Damascus, Syrian Arab Republic

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