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临床试验/NCT02340507
NCT02340507已完成不适用

The Impact of the Glycaemic Index (GI) on Daily Blood Glucose Profiles and Food Intake in Young Chinese Adult Males

Clinical Nutrition Research Centre, Singapore0 个研究点目标入组 15 人开始时间: 2013年5月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
15
主要终点
Glycaemic response (measured 3 hours post consumption using the Continuous Glucose Monitoring System (CGMS)

研究概览

简要总结

This study is carried out to find out the inclusion of high and low glycaemic Index (GI) foods to daily meals impact on 24 hour blood glucose fluctuations and food intake.

详细描述

The GI is a method of classifying foods based on the food's ability to raise the blood glucose level. Low GI foods are recommended as they have a lower impact on blood glucose concentrations and also reduce total food intake. There is very little information on how eating high and low GI foods affect daily blood glucose concentrations in Asians. Therefore, the objective of this study is to observe the effect of eating high and low GI breakfasts and snacks on 24 hour blood glucose concentrations and food consumption in Asian males. Healthy, normal-weight, Chinese males will be recruited. There will be two sessions (consisting of four days for each session) where they will consume either a high or low GI breakfast or snack, and a standardized ad libitum lunch buffet. Their glycaemic response will be measured using a Continuous Glucose Monitoring System (CGMS) throughout the period. The proposed research for the first time demonstrates how the consumption of high and low GI breakfasts and snacks affect subsequent energy intake and 24 hour blood glucose profiles in Asians. These findings will have significant public health benefits for optimum weight and dietary control.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
盲法
None

入排标准

年龄范围
21 Years 至 40 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • Chinese, male
  • Age between 21-40 years
  • Body mass index between 17 to 24 kg/m2
  • Normal blood pressure (120/80 Hgmm)
  • Fasting blood glucose < 6 mmol/L

排除标准

  • Having any metabolic diseases (such as diabetes, hypertension etc)
  • One prescription medication
  • Partaking in sports at the competitive and/or endurance levels
  • Allergic/intolerant to any of the test foods
  • Intentionally restricting food intake

结局指标

主要结局

Glycaemic response (measured 3 hours post consumption using the Continuous Glucose Monitoring System (CGMS)

时间窗: 3 hours post consumption

The blood glucose response to low and high GI test foods measured 3 hours post consumption using the Continuous Glucose Monitoring System (CGMS)

Daily blood glucose profile (easured for each low and high GI treatment as the area under the curve over 24 hours using CGMS)

时间窗: 24 hours

The daily total blood glucose response is measured for each low and high GI treatment as the area under the curve over 24 hours using CGMS.

次要结局

  • Energy intake (The amount of food consumed at the ad libitum lunch is measured by weighed quantities (in grams converted to kilocalories) based on the difference of the weight of food before and after consumption)(Immediately post meal consumption)

研究者

发起方
Clinical Nutrition Research Centre, Singapore
申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

JeyaKumar Henry

Principal Investigator

Clinical Nutrition Research Centre, Singapore

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