The Effect of Lactobacillus Reuteri on Lipid profile in Hypercholesterolemic Adults
Phase 3
- Conditions
- Hypercholesterolemia.Dietary counseling and surveillanceZ71.3
- Registration Number
- IRCT20231111060016N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
THE AGE OF OUR participant will be between 20 to 70 years old; their total cholesterol plasma level will be above 200 mg/dl; HDL-C plasma level under 70 mg/dl; BMI will be between 20 to 45 kg/m2; they should sign informed consent
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The percentage of patients calculated by SCORE in each group had LDL with a suitable range for lifestyle modification, in the patients of Cardiovascular Clinic of Qaem Hospital. Timepoint: The lipid profile of the patients is measured before the start of the study, 30 days and then 60 days after taking the drugs. Method of measurement: Initial lipid profile testing.
- Secondary Outcome Measures
Name Time Method Secondary effects:1-Percentage of acute coronary syndrome (ACS: Unstable angina, NSTEMI, STEMI)2- Percentage of incidence of metabolic syndrome (by examining each metabolic syndrome criteria: abdominal circumference, fasting blood sugar level, HDL level, TG level, blood pressure level) in future monthly visits3. The percentage of LDL serum levels of patients after the study. Timepoint: Before starting the study, 30 days later and then 60 days after taking the capsules. Method of measurement: Description of oral condition in the form of an interview for the occurrence of ACS - use of sphygmomanometer to measure blood pressure - use of routine lipid profile tests and fasting blood sugar.