Pre-ERCP High Carbohydrate Drinks Improve Patients Recovery
- Conditions
- Complication
- Interventions
- Procedure: 400ml high carbohydrate liquid diet before ERCP
- Registration Number
- NCT03075280
- Lead Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
- Brief Summary
To test the benefits of extra high carbohydrate liquid diet uptake 2 hours before ERCP in improving patients' early recovery.
- Detailed Description
Enhanced recovery after surgery (ERAS) has been formed of procedure which contains preoperative education, improvement of anesthesia, reducing the number of drainage tubes, and early diet after surgery. In recent years, because of its positive advantages, ERAS was widely accepted in surgical fields.
For upper gastrointestinal surgery, high-carbohydrate drinks can be given 2 hours before surgery in order to guarantee the stability of blood glucose and circulation during the operation. It obviously reduce the preoperative thirst, hunger, irritability and even the incidence of postoperative complications.
However ERAS program is rarely studied in ERCP. Theoretically we can use ERAS as a strategy to reduce post-ERCP uncomfortable and complications.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1292
- ERCP patients,
- Age 18-85 years old.
- Coagulation dysfunction (INR> 1.3) and low peripheral blood platelet count(<50×109 / L) or using anti-coagulation drugs,
- Preoperative coexistent diseases: acute pancreatitis, GI tract hemorrhage, severe liver disease, shock, liver or kidney malfunction,
- Diabetes（blood glucose fluctuations）or with complications,
- Intestinal obstruction or other contraindications with feeding and watering,
- Prior surgery of Bismuth Ⅱ and Roux-en-Y,
- Pregnant women,
- Unwillingness or inability to consent for the study.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description High carbohydrate liquid diet 400ml high carbohydrate liquid diet before ERCP No need preoperative fasting more than 6 hours. Uptake 400ml high carbohydrate liquid diet 2 hours before ERCP.
- Primary Outcome Measures
Name Time Method Abdominal pain 6 months Pain score (scores:1-10)
Levels of fatigue (Fatigue Scale-14 scoring system) 6 months The patients always feel tired and faint. The clinical manifestation includes slow to respond, the flexibility and coordination disorders.
- Secondary Outcome Measures
Name Time Method The time eating 6 months The time of eager to eat after procedure
The average incubation time 6 months The time of total procedure
Length of hospital stay 6 months Days of hospital stay
Successful cannulation time 6 months From first achieve the papilla to success cannulation
Postoperative abdominal distention 6 months Distention uncomfortable
Intraoperative residues in stomach 6 months The volume of stomach residues
Postoperative nausea and vomiting 6 months Nausea or vomiting after procedure
Complications 6 months Pancreatitis, cholangitis, bleeding, aspiration, et,al.
Blood glucose 6 months Intra-operative blood glucose and 2 hours' blood glucose after procedure
Trial Locations
- Locations (15)
Third Military Medical University
🇨🇳Chongqing, Chongqing, China
The first hospital of Lanzhou university
🇨🇳Lanzhou, Gansu, China
The Second Affiliated Hospital of Guangzhou Medical University
🇨🇳Guangzhou, Guangdong, China
The Second Hospital of Hebei Medical University
🇨🇳Shijiazhuang, Hebei, China
Tongji medical collage,Huazhong University of science and technology
🇨🇳Wuhan, Hubei, China
The First Hospital of Jilin University
🇨🇳Changchun, Jilin, China
General Hospital of Ningxia Medical University
🇨🇳Yingchuan, Ningxia, China
The first affiliated hospital of Xi 'an jiaotong university
🇨🇳Xi'an, Shaanxi, China
Shandong jiaotong Hospital
🇨🇳Jinan, Shandong, China
Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
🇨🇳Shanghai, Shanghai, China
Taiyuan Iron and Steel Corporation Hospital
🇨🇳Taiyuan, Shanxi, China
Tianjin Nankai Hospital
🇨🇳Tianjin, Tianjin, China
The First Teaching Hospital of Xinjiang Medical University
🇨🇳Ürümqi, Xinjiang, China
Shulan Hospital of Zhejiang University
🇨🇳Hangzhou, Zhejiang, China
Second Xiangya Hospital, Central South University
🇨🇳Changsha, Hunan, China