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Clinical Trials/NCT04587310
NCT04587310CompletedNot Applicable

Does Laparoscopic Sleeve Gastrectomy Lead to Barrett's Esophagus, 5-year Esophagogastroduodenoscopy Findings: A Retrospective Cohort Study

Eliana Al Haddad0 sites92 target enrollmentStarted: October 1, 2008Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
92
Primary Endpoint
endoscopy performed on patients

Study Overview

Brief Summary

Introduction Laparoscopic Sleeve Gastrectomy (LSG) is one of the most prevalent approaches to tackle obesity and its co-morbidities. The main complication following the LSG is Gastro-esophageal reflux disease (GERD), with most patients developing worsening symptoms of GERD, and a small number progressing to Barrett's esophagus. This retrospective analysis aims to assess the rate of GERD pre- and post- LSG as well as the rate of progression to Barrett's.

Methods Data was collected from 1639 patients. 92 patients fit our inclusion criteria. Data was then analyzed and summarized against similar literature

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Retrospective

Eligibility Criteria

Ages
24 Years to 36 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • patients eligible to sleeve gastrectomy that had an EGD pre and 5 years post-op

Exclusion Criteria

  • missing or implausible data, had multiple surgeries, and suffered from the common post-sleeve complications, such as leaks, strictures and hiatal hernias

Outcomes

Primary Outcomes

endoscopy performed on patients

Time Frame: 5 years

endoscopy will be performed on patients 5 years after undergoing sleeve gastrectomy due to the fact that sleeve tends to lead to reflux which causes dysplasia of esophageal cells, which eventually can lead to barrett's esophagus and cancer.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Eliana Al Haddad
Sponsor Class
Other
Responsible Party
Sponsor Investigator
Principal Investigator

Eliana Al Haddad

post-doc research fellow

Jaber Al Ahmad Al Sabah Hospital

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