EUCTR2010-019647-19-GB
Active, not recruiting
Not Applicable
A double blind randomised placebo controlled trial of montelukast in the treatment of acute persistent cough in young people and adults (aged 16-49) in primary care - Montelukast for persistent cough in young people and adults
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute persistent cough with no established diagnosis
- Sponsor
- niversity of Oxford
- Enrollment
- 260
- Status
- Active, not recruiting
- Last Updated
- 13 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\)Male or Female, aged 16 years to 49 years inclusive.
- •2\)Presenting with a persistent cough of 2\-8 weeks' duration without an established diagnosis (e.g. asthma, gastro\-oesophageal reflux).
- •3\)Able to complete cough diary and study questionnaires.
- •Are the trial subjects under 18? yes
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range
- •F.1\.3 Elderly (\>\=65 years) no
- •F.1\.3\.1 Number of subjects for this age range
Exclusion Criteria
- •The participant may not enter the study if ANY of the following apply:
- •1\)There is a contraindication to montelukast
- •2\)Chronic severe disease which may cause persistent cough (eg cystic fibrosis, bronchiectasis, cardiac failure)
- •3\)Immunodeficiency/immunocompromised state
- •4\)Pregnancy
- •5\)Breastfeeding
- •6\)Current smoker (i.e. stopped smoking less than 6 months ago).
- •7\)Regular medication associated with persistent cough (ACE inhibitors)
- •8\)The individual is in another clinical research study.
Outcomes
Primary Outcomes
Not specified
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