A double blind randomised placebo controlled trial of montelukast in the treatment of acute persistent cough in young people and adults (aged 16-49) in primary care - Montelukast for persistent cough in young people and adults

Active, not recruiting

• Conditions: Acute persistent cough with no established diagnosis

• Registration Number: EUCTR2010-019647-19-GB
• Lead Sponsor: niversity of Oxford

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-12-22
• Last Update Posted: 3 December 2012

Recruitment & Eligibility

• Status: Not Recruiting
• Sex: All
• Target Recruitment: 260

Inclusion Criteria

1)Male or Female, aged 16 years to 49 years inclusive.
2)Presenting with a persistent cough of 2-8 weeks' duration without an established diagnosis (e.g. asthma, gastro-oesophageal reflux).
3)Able to complete cough diary and study questionnaires.

Are the trial subjects under 18? yes
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

The participant may not enter the study if ANY of the following apply:
1)There is a contraindication to montelukast
2)Chronic severe disease which may cause persistent cough (eg cystic fibrosis, bronchiectasis, cardiac failure)
3)Immunodeficiency/immunocompromised state
4)Pregnancy
5)Breastfeeding
6)Current smoker (i.e. stopped smoking less than 6 months ago).
7)Regular medication associated with persistent cough (ACE inhibitors)
8)The individual is in another clinical research study.

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified