The Second Xiangya Hospital of Central South University
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Postoperative Progression-Free Survival
研究概览
简要总结
The objective of this observational study is to investigate the characteristics of the tumor microenvironment in patients with brain tumors using multi-modal magnetic resonance imaging (MRI). The primary research question it aims to address is:
• Can multi-modal MRI effectively characterize features of the immune microenvironment in brain tumor patients?
Participants:
Eligible participants who have been diagnosed with a brain tumor will undergo multi-modal MRI scans for detailed assessment of tumor microenvironment features.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •conventional MRI revealed intracranial space-occupying lesions and suspected high-grade gliomas, brain metastases and meningiomas；
- •It is planned to perform a brain tumor resection surgery in this institution.
排除标准
- •other CNS diseases in addition to brain tumors;
- •pathologically confirmed brain tumors not belonging to any of the three selected types;
- •contraindications to the use of gadolinium contrast, including hypersensitivity to contrast agents, renal dysfunction, pregnancy or lactation;
- •contraindications to MRI;
- •poor image quality unsuitable for subsequent analyses;
- •age younger than 18 years.
结局指标
主要结局
Postoperative Progression-Free Survival
时间窗: 6months，12months，24months
Postoperative Progression-Free Survival is defined as the time interval from the date of surgical intervention until the first occurrence of either documented disease progression or death from any cause
次要结局
未报告次要终点
研究者
Yu Zhou
Assistant Researcher
Second Xiangya Hospital of Central South University