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临床试验/NCT04657692
NCT04657692已完成不适用

Incidence of Complications Associated With Anesthesia in Obesity Parturient Undergoing Cesarean Delivery- a Retrospective Review

Mahidol University1 个研究点 分布在 1 个国家目标入组 527 人开始时间: 2020年12月29日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
527
试验地点
1
主要终点
Incidence of complications

研究概览

简要总结

The incidence of obesity parturient has been increasing worldwide. There was a report revealing one third of pregnant women in United state considered obesity.

Obesity is associated with increased in maternal and neonatal complications. Also, there was an increasing in the rate of cesarean delivery. Anesthetic management of the obese parturient is differ from non-obese parturients. There were higher risk of difficult intubation, failed intubation, pulmonary aspiration and difficult regional anesthesia such as spinal anesthesia or epidural catheter placement comparing with non-obese parturient.

The aim of the study is to report complication associated with anesthesia in obese patients undergoing cesarean delivery in Single University hospital, Bangkok, THAILAND.

详细描述

The incidence of obesity parturient has been increasing worldwide. There was a report revealing one third of pregnant women in United state considered obesity.

Obesity is associated with increased in maternal and neonatal complications. Also, there was an increasing in the rate of cesarean delivery. Anesthetic management of the obese parturient is differ from non-obese parturients. There were higher risk of difficult intubation and difficult regional anesthesia such as spinal anesthesia or epidural catheter placement comparing with non-obese parturient.

WHO categorised obesity into 3 classification; grade 1: BMI 30-34.9 kg/m2, grade 2: BMI 35-39.9 kg/m2, grade 3: BMI > 40 kg/m2. This study emphasised in grade 3 obese pregnant women (BMI>40 kg/m2) undergoing cesarean delivery that were at risk of increasing in anesthetic complications such as airway complications as well as complications derived from regional anesthesia eg. high spinal block, failed spinal block etc.

Therefore, the primary objective of the study is to report complication associated with anesthesia in obese patients undergoing cesarean delivery in Single University hospital, Bangkok, THAILAND. The secondary objectives rate of postpartum haemorrhage, rate of hysterectomy and neonatal outcomes.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Pregnant women BMI>,= 40 kg/m2 underwent cesarean delivery

排除标准

  • Patients with gestational age <,= 24 weeks
  • Patients with death fetus in Utero
  • Multiple gestation
  • Patients with intrapelvic cavity pathology eg. myoma uteri
  • Patients with abnormal placentation
  • Patients with polyhydramnios

结局指标

主要结局

Incidence of complications

时间窗: intraoperative period to 24 hours postoperative

Incidence of maternal complications associated with anesthesia

次要结局

  • Incidence of obstetric-related complications(intraoperative period to 24 hours postoperative)
  • Neonatal outcomes(Neonate apgar score at 1-min and 5 min)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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