Randomized double-blind comparative study on the effect of bifidobacterial on the low dose oral immunotherapy for egg allergy children.
Not Applicable
- Conditions
- Hen's egg allergy
- Registration Number
- JPRN-UMIN000033739
- Lead Sponsor
- Showa University, Department of pediatrics
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 48
Inclusion Criteria
Not provided
Exclusion Criteria
a) Of control poor atopic dermatitis or bronchial asthma b) Cardiovascular, cranial nerve, Renal urology, Hepatobiliary, pancreatic, gastrointestinal, etc, which are serious or have diseases which may affect research c) Implementing other immunotherapy d) Other test responsibilities(shared) patients judged inappropriate by the doctor as subjects
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The rate of 1/8 hen's egg tolerance at 32 weeks after intervention started
- Secondary Outcome Measures
Name Time Method The rate of 1/32 hen's egg desensitization at 32 weeks after intervention started. Objective indicater(blood:change in eosinophil count,total IgE,antien specific IgE(egg white,egg yolk,ovomucoid),antigen specific IgG4(egg white,ovomucoid),basophil stimulation test(OVM), faeces:intestinal flora, calprotectin,skin prick test) Side reaction rate on oral immunotherapy, Safety assessment(incidence of adverse events)