NCT03340649Unknown不适用
The Predictive Value of Hepatocyte Growth Factor and Soluble Receptor s-Met in Evaluating Sepsis Patient's Disease Severity and Prognosis
Jingyuan,Xu1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2017年11月9日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- mortality
研究概览
简要总结
To observe the changes of plasma hepatocyte growth factor and soluble receptor s-Met levels in patients with sepsis, and to explore its clinical significance.
详细描述
90 patients who diagnosed as sepsis were included in this study. Then keep blood samples from these patients in the first day, the third day, detect the hepatocyte growth factor and soluble receptor s-Met level in plasma byenzyme-linked immuno sorbent assay. Record Severity of illness and survival status of every patient within 28 days. Objective to evaluate the correlation between the level of hepatocyte growth factor and soluble receptor s-Met in plasma and the prognosis of the patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients admitted to ICU diagnosed of sepsis(sepsis3.0 criteria)
- •Patients signing informed consent
排除标准
- •Age is less than 18 years old or more than 80 years old
- •Pregnant women
- •Patients with tumor、hepatitis、liver cirrhosis、acute myocardial infarction、chronic renal tubular nephritis、interstitial pneumonia、acute pancreatitis、systemic lupus erythenatosus、ulcerative colitis、crohn's disease、HELLP syndrome
- •Prothrombin time is extension in patients with after liver transplantation
- •Patients with chronic renal failure
- •Patients after kidney transplantation
结局指标
主要结局
mortality
时间窗: 28-day
28-day mortality
次要结局
未报告次要终点
研究者
Jingyuan,Xu
Attending doctor
Southeast University, China
研究点 (1)
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