NCT01601223已完成不适用
Local Assessment of Ventilatory Management During General Anesthesia for Surgery - a Prospective Observational Multi-center Cohort Study
European Society of Anaesthesiology19 个研究点 分布在 8 个国家目标入组 10,690 人开始时间: 2013年1月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10,690
- 试验地点
- 19
- 主要终点
- Post-operative pulmonary complications, possibly related to ventilation strategy
研究概览
简要总结
Objectives
- To characterize mechanical ventilation practices during general anesthesia for surgery
- To assess the dependence of intra-operative and post-operative pulmonary complications on intra-operative Mechanical Ventilation (MV) settings
详细描述
Research questions
- What MV-settings are used during general anesthesia for surgery?
- Do MV-settings vary in and/or between centers?
- Do MV-settings vary internationally?
- Are MV-settings associated with incidence of intra-operative pulmonary complications?
- Are MV-settings associated with incidence of post-operative pulmonary complications?
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years
- •All surgical procedures requiring invasive mechanical ventilation (MV)during general anesthesia for laparoscopic or non-laparoscopic surgery.
- •This includes MV performed with supra-glottic devices (e.g. laryngeal mask)
- •This includes patients receiving MV at the onset of the procedure (e.g. Intensive Care Unit patients)
- •This includes patients who will receive one-lung ventilation during the procedure
排除标准
- •Obstetric surgical procedures or any procedure during pregnancy
- •Surgical procedures outside the operating room
- •Surgical procedures involving extra-corporal circulation
结局指标
主要结局
Post-operative pulmonary complications, possibly related to ventilation strategy
时间窗: Post-operative on day of surgery, day 1, 2,3,4,5 and day 28
Effect of Mechanical Ventilation settings during general anesthesia for surgery on the incidence of post-operative pulmonary complications (new or prolonged invasive or non-invasive mechanical ventilation, need for oxygen therapy, respiratory failure, pneumonia, ARDS 'Acute Respiratory Distress Syndrome', pneumothorax) Defined post-operative pulmonary complications are recorded from the medical chart on day 0, 1, 2, 3, 4 and 5 after surgery. On day 28 length of hospital stay and in hospital death are assessed.
次要结局
- Mechanical ventilation-settings during general anesthesia for surgery(During the surgical procedure, from moment of to tracheal extubation or discharge from operation room (in case patient remains on mechanical ventilation))
- Intra-operative complications related to the ventilation strategy(Time point(s) at which outcome measure is assessed is is: Day of surgery, day 1, 2, 3, 4, 5 and 28 after surgery)
研究者
研究点 (19)
Loading locations...
相似试验
已完成
不适用
Ventilation's Parameters Applied in Emergency Medicine. A Prospective Observational StudyMechanical VentilationProtective VentilationSurvivalAcute Respiratory Distress SyndromeNCT03351920Poitiers University Hospital229
已完成
不适用
Assessment of Ventilatory Management During General Anesthesia for Robotic SurgeryRobotic SurgeryMechanical VentilationNCT02989415Hospital Israelita Albert Einstein1,015
招募中
不适用
Mechanical Ventilation in Surgical PatientsSurgeryVentilator LungPostoperative ComplicationsNCT06296277Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria10,000
招募中
不适用
Ventilatory Settings and Monitoring Variables Associated With Weaning Failure in Critically Ill PatientsMechanical VentilationWeaning FailureWeaning Failure of Mechanical VentilationIntensive Care Unit ICUNCT06683781Hospital Italiano de Buenos Aires1,077
已完成
不适用
Ventilation Strategy During General Anesthesia for Orthopedic Surgery: A Quality Improvement ProjectOrthopedic SurgeryVentilationNCT03657368The Cleveland Clinic2,860