Local Assessment of Ventilatory Management During General Anesthesia for Surgery - a Prospective Observational Multi-center Cohort Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Surgery
- Sponsor
- European Society of Anaesthesiology
- Enrollment
- 10690
- Locations
- 19
- Primary Endpoint
- Post-operative pulmonary complications, possibly related to ventilation strategy
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
Objectives
- To characterize mechanical ventilation practices during general anesthesia for surgery
- To assess the dependence of intra-operative and post-operative pulmonary complications on intra-operative Mechanical Ventilation (MV) settings
Detailed Description
Research questions * What MV-settings are used during general anesthesia for surgery? * Do MV-settings vary in and/or between centers? * Do MV-settings vary internationally? * Are MV-settings associated with incidence of intra-operative pulmonary complications? * Are MV-settings associated with incidence of post-operative pulmonary complications?
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age ≥ 18 years
- •All surgical procedures requiring invasive mechanical ventilation (MV)during general anesthesia for laparoscopic or non-laparoscopic surgery.
- •This includes MV performed with supra-glottic devices (e.g. laryngeal mask)
- •This includes patients receiving MV at the onset of the procedure (e.g. Intensive Care Unit patients)
- •This includes patients who will receive one-lung ventilation during the procedure
Exclusion Criteria
- •Obstetric surgical procedures or any procedure during pregnancy
- •Surgical procedures outside the operating room
- •Surgical procedures involving extra-corporal circulation
Outcomes
Primary Outcomes
Post-operative pulmonary complications, possibly related to ventilation strategy
Time Frame: Post-operative on day of surgery, day 1, 2,3,4,5 and day 28
Effect of Mechanical Ventilation settings during general anesthesia for surgery on the incidence of post-operative pulmonary complications (new or prolonged invasive or non-invasive mechanical ventilation, need for oxygen therapy, respiratory failure, pneumonia, ARDS 'Acute Respiratory Distress Syndrome', pneumothorax) Defined post-operative pulmonary complications are recorded from the medical chart on day 0, 1, 2, 3, 4 and 5 after surgery. On day 28 length of hospital stay and in hospital death are assessed.
Secondary Outcomes
- Mechanical ventilation-settings during general anesthesia for surgery(During the surgical procedure, from moment of to tracheal extubation or discharge from operation room (in case patient remains on mechanical ventilation))
- Intra-operative complications related to the ventilation strategy(Time point(s) at which outcome measure is assessed is is: Day of surgery, day 1, 2, 3, 4, 5 and 28 after surgery)