NCT01604798
Completed
Not Applicable
Serum Proteomic Profiling for the Early Diagnosis of Colorectal Cancer
ConditionsColorectal Neoplasms
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Colorectal Neoplasms
- Sponsor
- Fudan University
- Enrollment
- 547
- Locations
- 1
- Primary Endpoint
- Serum peptide mass fingerprinting (PMF)
- Status
- Completed
- Last Updated
- 13 years ago
Overview
Brief Summary
No ideal serum biomarker currently exists for the early diagnosis of colorectal cancer (CRC). Therefore, it is urgent that accurate and reliable serum biomarkers be identified.
Detailed Description
Magnetic bead-based fractionation coupled with matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry (MALDI-TOF MS) was used to screen serum samples from CRC patients and healthy controls.
Investigators
Xu jianmin
Professor of General Surgery
Fudan University
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Serum peptide mass fingerprinting (PMF)
Time Frame: 2010.03-2012.05 (2 years)
Compare PMF of the colorectal caner group and control group, and then build the model to distinguish patients with colorectal cancer and controls
Secondary Outcomes
- Expressed peptide peaks(2010.03-2012.05 (2 years))
Study Sites (1)
Loading locations...
Similar Trials
Completed
Not Applicable
Predicting Response to Chemotherapy in Colorectal Cancer Via Multi-dimensional Analyses of the Tumor Associated NeutrophilsTumor Associated NeutrophilsNCT06495827Fudan University653
Completed
Not Applicable
Blood Proteins in Finding Pancreatic Cancer and Extrahepatic Biliary Tract CancerExtrahepatic Bile Duct CancerPancreatic CancerNCT00559598National Institutes of Health Clinical Center (CC)502
Completed
Not Applicable
Identification of New Diagnostic Protein Markers for Colorectal CancerColorectal CancerNCT04394572CHU de Reims80
Unknown
Not Applicable
Diagnosis of colorectal cancer by serum and exosomal CEA family and detection of circulating tumo cellsJPRN-UMIN000013680Wakayama Medical University, School of Medicine1,000
Recruiting
Phase 1
Blood biomarker of colorectal adenoma and early-stage adenocarcinomaJPRN-UMIN000033806Fujita Health University School of Medicine, Department of Gastroenterology200