CCTAP: Cognitive Control Training for Treatment of AUD-PTSD
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 9
- 试验地点
- 2
- 主要终点
- Acceptability
研究概览
简要总结
The primary objective of this study is to evaluate the feasibility of the revised brain training program with individuals diagnosed with Alcohol Use Disorder (AUD) and Post-Traumatic Stress Disorder (PTSD).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participant is a Veteran and is enrolled in outpatient Substance Use Disorder treatment within Veteran Affairs Palo Alto Health Care System
- •Participant meets Diagnostic and Statistical Manual of Mental Disorders-5 criteria for current Alcohol Use Disorder and seeking treatment for Alcohol Use Disorder
- •Participant meets Meet Diagnostic and Statistical Manual of Mental Disorders-5 criteria for current PTSD
- •Participant must be willing to perform daily home-based computer exercises for 6 weeks
- •Participant must demonstrate mild cognitive deficit on neuropsychological tests at the screening visit
- •Participant must be a fluent English speaker from the age of 12
- •Participant must have adequate sensorimotor capacity to perform the program, including visual capacity adequate to read from a iPad screen at a normal viewing distance, auditory capacity adequate to understand normal speech, and motor capacity adequate to control a touchpad
排除标准
- •Participant with diagnosis of an illness or condition with known cognitive consequences (e.g., schizophrenia, bipolar disorder, cancer, multiple sclerosis, Traumatic Brain Injury, mental retardation or pervasive developmental disorder, epilepsy, Parkinson's Disease, delirium or dementia)
- •Participant with active suicidal ideations as measured by the Columbia-Suicide Severity Rating Scale (C-SSRS)
- •Participant with problems performing assessments or comprehending or following spoken instructions
- •Participant who has been treated within 5 years of the date of consent with a computer-based cognitive training program manufactured by Posit Science
- •Participant with current severe traumatic brain injury
- •Participant with any type of dementia
- •Participant with any type of mental retardation
- •Participant with limited ability to speak/read/write/understand English
研究组 & 干预措施
Experimental Treatment
Computerized plasticity-based adaptive cognitive training requiring a total maximum of 30 treatment sessions, up to 5 sessions per week, 30 minutes per session.
干预措施: Computerized Plasticity-Based Adaptive Cognitive Training (Other)
结局指标
主要结局
Acceptability
时间窗: At 6 weeks
Acceptability will be evaluated through Cognitive Training Acceptability Measure. This measure is comprised of 17 statements about their training experience and participants will be asked to rate each statement on a 7-point Likert scale from Strongly Disagree to Strongly Agree.
Usability
时间窗: At 6 weeks
Usability will be evaluated through the Computer System Usability Questionnaire and System Usability Scale. The Computer System Usability Questionnaire and System Usability Scale is comprised of a total of 29 statements and participants will be asked to rate the usability of the system on a 7-point Likert scale from Strongly Disagree to Strongly Agree.
次要结局
未报告次要终点