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Clinical Trials/NCT03200028
NCT03200028
Completed
Not Applicable

CCTAP: Cognitive Control Training for Treatment of AUD-PTSD

Posit Science Corporation1 site in 1 country9 target enrollmentApril 1, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Alcohol Use Disorder
Sponsor
Posit Science Corporation
Enrollment
9
Locations
1
Primary Endpoint
Acceptability
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The primary objective of this study is to evaluate the feasibility of the revised brain training program with individuals diagnosed with Alcohol Use Disorder (AUD) and Post-Traumatic Stress Disorder (PTSD).

Registry
clinicaltrials.gov
Start Date
April 1, 2018
End Date
February 28, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Participant is a Veteran and is enrolled in outpatient Substance Use Disorder treatment within Veteran Affairs Palo Alto Health Care System
  • Participant meets Diagnostic and Statistical Manual of Mental Disorders-5 criteria for current Alcohol Use Disorder and seeking treatment for Alcohol Use Disorder
  • Participant meets Meet Diagnostic and Statistical Manual of Mental Disorders-5 criteria for current PTSD
  • Participant must be willing to perform daily home-based computer exercises for 6 weeks
  • Participant must demonstrate mild cognitive deficit on neuropsychological tests at the screening visit
  • Participant must be a fluent English speaker from the age of 12
  • Participant must have adequate sensorimotor capacity to perform the program, including visual capacity adequate to read from a iPad screen at a normal viewing distance, auditory capacity adequate to understand normal speech, and motor capacity adequate to control a touchpad

Exclusion Criteria

  • Participant with diagnosis of an illness or condition with known cognitive consequences (e.g., schizophrenia, bipolar disorder, cancer, multiple sclerosis, Traumatic Brain Injury, mental retardation or pervasive developmental disorder, epilepsy, Parkinson's Disease, delirium or dementia)
  • Participant with active suicidal ideations as measured by the Columbia-Suicide Severity Rating Scale (C-SSRS)
  • Participant with problems performing assessments or comprehending or following spoken instructions
  • Participant who has been treated within 5 years of the date of consent with a computer-based cognitive training program manufactured by Posit Science
  • Participant with current severe traumatic brain injury
  • Participant with any type of dementia
  • Participant with any type of mental retardation
  • Participant with limited ability to speak/read/write/understand English

Outcomes

Primary Outcomes

Acceptability

Time Frame: At 6 weeks

Acceptability will be evaluated through Cognitive Training Acceptability Measure. This measure is comprised of 17 statements about their training experience and participants will be asked to rate each statement on a 7-point Likert scale from Strongly Disagree to Strongly Agree.

Usability

Time Frame: At 6 weeks

Usability will be evaluated through the Computer System Usability Questionnaire and System Usability Scale. The Computer System Usability Questionnaire and System Usability Scale is comprised of a total of 29 statements and participants will be asked to rate the usability of the system on a 7-point Likert scale from Strongly Disagree to Strongly Agree.

Study Sites (1)

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