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Clinical Trials/NCT02828488
NCT02828488
Active, not recruiting
Not Applicable

Analysis of the Impact of the Fragility of the Over 70 Years of TIA (Transient Ischemic Attack) Prognosis

Fondation Hôpital Saint-Joseph1 site in 1 country110 target enrollmentAugust 6, 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Vascular
Sponsor
Fondation Hôpital Saint-Joseph
Enrollment
110
Locations
1
Primary Endpoint
Fried Score for fragility
Status
Active, not recruiting
Last Updated
3 years ago

Overview

Brief Summary

Fragility, geriatric concept recent identification is defined by simple physical indicators. The literature suggests that it is related to the risk of hospitalization, falls, institutionalization and death. Some studies have shown a link with heart disease, including heart failure. The link with the TIA (transient ischemic attack) has however never been studied. A fortiori, the impact of the fragility of the risk of recurrent stroke after TIA is unknown.

Several questions need to be asked: Among older patients hospitalized for TIA, what proportion of those completing the criteria of frailty? In this same population, is there a correlation between fragility and scores ABCD2 score itself predictive of the risk of subsequent ischemic stroke? In other words, fragile subjects who have a TIA Have a higher risk of ischemic stroke (which could cause a strengthening of prevention measures)?

Detailed Description

Hypotheses : * Frailty is common among the elderly patient population who have a TIA. Compared to control groups of literature. * Patients with high fragility score ABCD2 also have a high score. * Patients with a high score of fragility also have a significant number of vascular risk factors (including atrial fibrillation) * Patients with a high score of fragility also have an average length of stay (ALOS) higher than the others. So underlying the question is: can we learn to better identify patients who are going to need a bigger structure their output at home. objectives: * Assess the feasibility of placing a fragile test in acute phase of AIT in USINV. * To evaluate the frequency of frailty among the population of elderly patients who have a TIA. * Compare in AIT over 70 years those with fragile high score to those with low scores, especially for ABCD2 score, vascular risk factors and the DMS. * Statements parameters: o The fragility score: * Choice of fragility score: among the fragility of scores, the most used in international literature is the score of Linda Fried. Moreover, the stress of the study is related to the environment of the USINV (shortly, short DMS, often tired patients). It is therefore important to use this study for a test only, but quick handover. The score Fried also has the advantage (J Gerontol A Biol Sci Med Sci 2001, 56 (3): M146-56) The first 4 items are simple clinical evaluation. The 5th (grip test) will be performed with a device (single gauge measuring the fingers bending strength) loan from the geriatric ward.

Registry
clinicaltrials.gov
Start Date
August 6, 2015
End Date
December 31, 2023
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • The TIA is defined pragmatically: any sudden deficit with blood systematization ≤ 1 hour. Among these "TIA", we know that a subgroup may possibly have an MRI with diffusion lesion, indicating a recent ischemic stroke. This subgroup of transient accident is recognized as being at higher risk of recurrence. This criterion will be taken into account in the data analysis.

Exclusion Criteria

  • history of stroke with Rankin score of ≥
  • Severe depression
  • evolutionary Cancer
  • Heart Failure

Outcomes

Primary Outcomes

Fried Score for fragility

Time Frame: Day 1

Secondary Outcomes

  • ABCD Score(Day 1)

Study Sites (1)

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