Target Site Pharmacokinetics of Doripenem at Steady State in Intubated Intensive Care Patients

Completed

• Conditions: Pneumonia; Urinary Tract Infection; Abdominal Infection

• Registration Number: NCT01414959
• Lead Sponsor: Medical University of Vienna

Brief Summary

The investigators will measure the pharmacokinetics of doripenem in skeletal muscle, subcutaneous adipose tissue, bronchoalveolar lavage and plasma of intubated intensive care patients.

Detailed Description

Methods: microdialysis, blood sampling, bronchoalveolar lavage

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2011-08
• Study First Submitted: 2011-08-10
• Study First Submitted QC: 2011-08-10
• Study First Posted: 2011-08-11
• Primary Completion: 2013-07
• Study Completion: 2013-07
• Status Verified: 2017-08
• Last Update Submitted: 2017-08-28
• Last Update Posted: 2017-08-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• endotracheal intubation; pneumonia or complicated abdominal infection or complicated urinary tract infection

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Exclusion Criteria

• allergy to doripenem, hemodialysis

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Med. Univ. of Vienna; 🇦🇹 Vienna, Austria