The effect of single dose ketamine injection on reducing acute suicidal thoughts

Phase 3

• Conditions: Condition 1: Suicide. Condition 2: Major depressive disorde.; Suicide attempt; Major depressive disorder, single episode, severe without psychotic features; T14.91; F32.2

• Registration Number: IRCT20220118053756N1
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 27 June 2022

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

Clients with acute suicidal ideation (thoughts that have occurred within the last 72 hours and have not existed before, with serious risk and require psychiatric hospitalization)
Age range of 18-68 years old

Exclusion Criteria

physical disorders such as thyroid dysfunction, diabetes, hypertension, stroke and brain surgery and other neurological disorders
History of abuse or allergy to ketamine or midazolam
Pregnant and lactating women
Convulsion
current or recent and regular antidepressant medication last month

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Beck suicidal questionnaire score. Timepoint: Before injection; after 12 hours; 24 hours later. Method of measurement: Beck suicidal questionnaire.

Secondary Outcome Measures

Name	Time	Method
Score of visual analog scale for suicidal ideation. Timepoint: Before injection; 12 hours and 24 hours after injection. Method of measurement: Self reporting by patient.