MedPath

Sleep to Activate Mood Promotion

Not Applicable
Completed
Conditions
Depression
Sleep Quality
Interventions
Device: Re-Timer glasses
Registration Number
NCT02413294
Lead Sponsor
University of Michigan
Brief Summary

The investigators are aiming to examine the acceptability and feasibility of a portable bright light therapy instrument to improve sleep disturbance in a preventive intervention for depression. The investigators will conduct an intervention that trials the use of bright light glasses called "re-timers" as a preventive intervention in older adults with sleep disturbance and subsyndromal symptoms of depression.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
12
Inclusion Criteria
  • 65 years of age or older
  • 6 or greater on the Pittsburgh Sleep Quality Index
  • A score of 5 to 9 on the Patient Health Questionnaire-9 Depression Scale
Read More
Exclusion Criteria
  • Active suicidal ideation
  • Presence of mania or bipolar disorder
  • Presence of an eye disease
  • Prescription of a photosensitizing medication
  • Having previously had eye surgery
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Bright Light InterventionRe-Timer glassesBefore the bright light intervention is initiated (and during the intervention), participants will wear two wrist bands which measure sleep quality and activity levels- the Fitbit and actigraphy watches. These will be worn for two weeks to assess individuals' baseline levels of sleep quality and will continue to be worn during the intervention. Following the baseline period, the re-timer glasses will be introduced and worn for a period of 30 to 50 minutes a day for two weeks.
Primary Outcome Measures
NameTimeMethod
Patient Health Questionnaire-9 Depression Scaletwo weeks after introduction of intervention

The PHQ-9 Depression Scale is a validated scale ranging from 0 to 27 with higher numbers representing greater severity of depressive symptoms, based on 9 questions with each question on a scale of 0 - 3.

Insomnia Severity Index Sum Scorestwo weeks after introduction of intervention

The Insomnia Severity Index measures insomnia severity on a scale from 0 to 28. A score of 15 or higher is indicative of clinical insomnia.

Pittsburgh Sleep Quality Indextwo weeks after introduction of intervention

The Pittsburgh Sleep Quality Index is a validated scale which measures self-reported sleep quality based on a wide variety of questions (duration, quality, disturbances, medication, etc.) and converts them to a scale which ranges from 0 to 21 where 6 or higher denotes poor sleep quality.

Morningness-Eveningness Questionnairetwo weeks after introduction of intervention

The morningness- eveningness categories represent the time of day when a person is at their peak alertness.

Secondary Outcome Measures
NameTimeMethod
Actigraph Sleep Data: Minutes Asleepdaily for 4 weeks- baseline and intervention period

mean nightly sleep duration for each of the two-week periods: baseline and intervention

Actigraph: Number of Awakeningsdaily for 4 weeks- baseline and intervention period

Actigraphy counts awakenings by using an accelerometer to assess motion during the night. The number of awakenings is the mean nightly number of awakenings during each of the two-week periods: baseline and intervention.

Self-Reported Sleep Diary: Night Awakeningsdaily for 4 weeks- baseline and intervention period to be compared

mean number of night awakenings per person per night as reported in sleep diaries

Self-Reported Sleep Diary: Time at Which Participants Wake updaily for 4 weeks- baseline and intervention period to be compared

Wake time represents the moment in time at which participants awaken. Time between actual hours is calculated on a decimal basis so an additional 6 minutes = .1. so that 7.5 represents 7:30 a.m. and 7.8 represents 7:48 a.m.

Self-Reported Sleep Diary: Sleep Qualitydaily for 4 weeks- baseline and intervention period to be compared

sleep quality is a participants' mean self-report for each of the two week periods: baseline and intervention. Sleep quality is reported for each night on a scale of 0 (very poor) to 4 (very good).

Fitbit Sleep Data: Night Awakeningsdaily for 4 weeks- baseline and intervention period

mean nightly awakenings for each of the two week periods: baseline and intervention. Similar to the actigraph the Fitbit counts awakenings through an accelerometer which measures motion.

Fitbit Sleep Data: Sleep Efficiencydaily for 4 weeks- baseline and intervention period

Sleep efficiency is calculated as a percentage reflecting the amount of time in bed spent asleep (time asleep/time in bed x 100).

Self-Reported Sleep Diary: Time at Which Participants go to Beddaily for 4 weeks- baseline and intervention period to be compared

Bed time represents the moment in time at which participants went to bed, measured on a revised clock where 6pm = 18, Midnight = 24 and 6am =30. Time between actual hours is calculated on a decimal basis, so an additional 6 minutes = .1. This revised clock is necessary in order to make means work properly in the nighttime hours. Otherwise, averaging between a 10pm bedtime and a 2am bedtime would give the impossible, inaccurate mean of being in the daytime between those two numbers.

Self-Reported Sleep Diary: Sleep Durationdaily for 4 weeks- baseline and intervention period to be compared

nightly mean of length of sleep measured in minutes

Actigraph: Efficiencydaily for 4 weeks- baseline and intervention period

Sleep efficiency is calculated as a percentage reflecting the amount of time in bed spent asleep (time asleep/time in bed x 100). The mean for each of the two-week periods: baseline and intervention, is calculated.

Fitbit Sleep Data: Sleep Durationdaily for 4 weeks- baseline and intervention period

mean nightly sleep duration in minutes for each of the two-week periods: baseline and intervention

Trial Locations

Locations (1)

University of Michigan

🇺🇸

Ann Arbor, Michigan, United States

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