Prediction of Flucloxacillin Absorption and %time/MIC using the Flucloxacillin absorption test

Recruiting

• Conditions: absorption of flucloxacillin; resorption of flucloxacillin; 10004018

• Registration Number: NL-OMON55269
• Lead Sponsor: Haaglanden Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

>=18 years
Admitted to the hospital, during inclusion
S aureus infection with continuous infusion of flucloxacillin
Clinically eligible to be switched to oral flucloxacillin

Exclusion Criteria

ICU admittance
Pregnancy

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The prediction of time above MIC of both the 3 point concentration<br /><br>curves and 7 point concentration curves per patient before and after<br /><br>switch to oral flucloxacillin will be compared. > 50% time above MIC is<br /><br>considered sufficient</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Our secondary objective is to identify co-variants in order to improve the<br /><br>predictability, optimize and/or simplify the test.</p><br>