Comparison of Clinical Outcome Among Vaccinated and Unvaccinated Coronavirus Disease Patients Admitted to Critical Care Unit in a Tertiary Care Hospital of Kathmandu, Nepal.
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 200
- 主要终点
- Mortality
研究概览
简要总结
Corona virus disease has been a pandemic since its beginning. The problem has scaled to break health care system of multiple countries. One of the prime strategy of preventing this disease has been large mass scale vaccination campaign ongoing worldwide. No vaccine has been proven to 100 percent effective in preventing the infection with coronavirus disease so far. The investigators are conducting a study comparing outcome among vaccinated and unvaccinated population admitted to critical care unit of civil services hospital, Kathmandu , Nepal .
详细描述
Coronavirus disease has been a pandemic since its beginning. The problem has scaled up and health care system of multiple countries have reached to a breaking point . One of the prime strategy of preventing this disease has been large mass scale vaccination campaign ongoing worldwide. No vaccine has been proven to 100 percent effective in preventing the infection with coronavirus disease so far. The investigators are conducting a study comparing difference in outcome with regard to mortality and length of critical care unit stay among vaccinated and unvaccinated population admitted to critical care unit of civil services hospital , Kathmandu , Nepal.
Since different groups of population received different vaccine according to age profession and other factors investigators are trying to study the effectiveness of vaccine with regards to type of vaccine.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Crossover
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients proven to have covid 19 infection patients more than 18 years of age patients admitted to critical care unit
排除标准
- •patient below 18 years of age patients who do not have covid 19 infection
研究组 & 干预措施
vaccinated
patient between age 18 and above who have received a complete dose of coronavirus disease vaccine patient who has been admitted to critical care unit due to corona virus disease infection
干预措施: Vaccine (Drug)
结局指标
主要结局
Mortality
时间窗: within 12 weeks from the date of critical care unit admission
the primary outcome to be measured will be difference in mortality among two groups (vaccinated and unvaccinated) of coronavirus infected patients admitted in critical care unit
length of icu stay
时间窗: with 12 weeks from the date of critical care unit admission
difference in length of stay between vaccinated and unvaccinated population admitted to critical care unit after being infected with coronavirus disease
次要结局
- difference in mortality due to associated co-morbidity(within 24 weeks form the date of critical care unit admission)
研究者
Dr Deepak Bhandari
Registrar
Civil Service Hospital of Nepal