Platelet Rich Plasma Gel in Wound Closure in Recurrent Cesarean Section:Randomized Controlled Trial
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 128
- 试验地点
- 1
- 主要终点
- Efficacy of PRP in Wound healing in cesarean section by 100 mm visual analog scale
研究概览
简要总结
There is limited application of the use of PRP in obstetrics, therefore there is a need for assessment if it is efficacy in improving skin wound healing in cesarean section.
详细描述
This study aims to assess the efficacy of injection of platelet rich plasma into the wound of recurrent cesarean section for improving wound healing and enhancing the shape of the wound in women undergoing cesarean section.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 25 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •elective cesarean section
- •Body mass index 18:25
- •Hemoglobin more than 10.5 g/d
- •Albumin within normal more than or equal 3.5 g/d
排除标准
- •medical disorders(Diabetes mellitus,heart disease,hypertension,systemic lupus erythematosus)
- •high risk pregnancy as (placenta previa,placenta accreta)
- •patient on corticosteroids medication
- •primigravida subjected cesarean section
- •complicated cesarean section (increased operation time,blood transfusion, drain, scrubbing of multiple surgeons)
- •cesarean section due to chorioaminionitis
- •postoperative complication such as:postpartum hemorrhage, paralytic ileus, sever distention..) will be dropped out from the study
研究组 & 干预措施
platelet rich plasma gel
Injection of Platelet rich plasma (PRP) gel in 64 cases at time of wound closure in women undergoing cesarean section for improving wound healing after fullfit to all the inclusion and exclusion craiteria
干预措施: platelet rich plasma gel (Biological)
Saline
64 Controlled Women with recurrent cesarean section and fullfit to all the inclusion and exclusion craiteria will reseve saline injection at time of wound closure
干预措施: saline (Biological)
结局指标
主要结局
Efficacy of PRP in Wound healing in cesarean section by 100 mm visual analog scale
时间窗: one month
Efficacy of PRP in Wound healing in cesarean section by 100 mm visual analog scale (VAS) for wound healing
次要结局
- Assessment of the Cosmetic results of the wound by Modified Vancouver scar scale(one month)
研究者
rasha medhat abdul-hady
Dr.
Ain Shams University