Efficacy and safety study of Bethanechol chloride (75mg/150mg daily dose) in Indian patients with underactive bladder (UAB): A Prospective, Observational, Non-comparative study

Ranchi Urology Center (RUC)0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年5月29日

试验速览

暂无简介。

•1. Male and female patients above 18 years at the time of signing the informed consent
•2. Subject diagnosed with underactive bladder (UAB)
•3. Patients with underactive bladder (UAB) meeting the below criteria for impaired detrusor contractility and no obstruction based on
•uroflowmetry and urodynamic study (Pressure - Flow study):
•e. The Bladder Contractility Index
•f. The Bladder Outlet Obstruction Index (BOOI)
•4. Patients with controlled hypertension and type 2 diabetes mellitus will also be considered for the study

•1. Impaired detrusor contractility due to causes like complete spinal cord lesions, post-operative, and post pregnancy
•2. With bladder outlet obstruction as determined by a urodynamic study, including a pressure/flow study
•3. With detrusor-external sphincter dyssynergia determined by a urodynamic study and with external sphincter electromyography
•4. On medication with anticholinergics, other alfa-antagonists, or beta-agonists or antagonists
•5. Patients with compromised liver and renal function
•6. Patients in whom bethanechol is contraindicated as per the prescribing information
•7. Patients with diabetic neuropathy, glaucoma, abdominal cramps, and inflammation will not be included in the study.

发起方

Ranchi Urology Center (RUC)