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Clinical Trials/NCT03051776
NCT03051776
Completed
Not Applicable

Kinesio Taping Versus Compression Garments in the Treatment of Breast Cancer-Related Lymphedema. Randomized Crossover Trial.

Violeta Pajero Otero1 site in 1 country30 target enrollmentStarted: January 3, 2016Last updated:

Overview

Phase
Not Applicable
Status
Completed
Sponsor
Violeta Pajero Otero
Enrollment
30
Locations
1
Primary Endpoint
Estimated volumen of the upper limb.

Overview

Brief Summary

Breast cancer-related lymphedema (BCRL) tends to become chronic and progressive. Current therapies have modest results for this condition. Compression garments (CG) prevent the worsening of lymphedema and even improve it, during periods between treatments of physical therapy. Kinesio Taping(KT) is being recently used for lymphedema, although little evidence backs it. The aim of this study is to compare the reduction of lymphedema volume with both therapies.

Detailed Description

Primary end points: to evaluate whether the decrease in BCRL volume is different for a 4-week treatment with KT than with CG.

Research design:

Randomized quasi-experimental clinical pilot study: initial sample randomly balanced into two groups . The initial sample was selected among the patients of "Breast Pathology Rehabilitation" at Hospital Universitario 12 de Octubre . The planned sample size was 30.

Cross Design: it made possible to evaluate two different treatments in the same patient, cancelling intragroup variability.

Open design: it was impossible to blind patients and physiotherapist researcher because of patent visual differences between the two therapies, CG or KT, both during application and while being worn, and even in the hours after its removal, due to the marks left on the skin. However, at least one external evaluator suitably trained was implemented and performed the randomisation of the groups and collected all patient data. Statistical study was also made by others (staff of the "Clinique Investigation Unit (i+12)" of Hospital Universitario 12 de Octubre) with coded variables to blind the analyst.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover
Primary Purpose
Treatment
Masking
Single (Outcomes Assessor)

Masking Description

The statistical analysis will be supervised by staff of the Scientific Support Unit: Epidemiology and Biostatistics (i+12), Hospital Universitario 12 de Octubre with the variables coded to blind the analyst.

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
Female
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Suffering from clinically significant breast cancer-related lymphedema at least since three months ago.
  • Having a Compression Garment suitable for the lymphedema arm

Exclusion Criteria

  • Physiotherapy treatment for lymphedema during the 4 weeks before study start (pre-wash phase).
  • Metastasis breast cancer or other tumour.
  • Treated with systemic chemotherapy and /or radiotherapy at that time
  • Heart Failure or Renal Failure.
  • Using Diuretics.
  • Bilateral axillary lymphadenectomy.
  • Cognitive impairment or delay that impedes understanding the study's instructions.

Outcomes

Primary Outcomes

Estimated volumen of the upper limb.

Time Frame: Four weeks during each treatment phase

Truncated Cone Formula.

Secondary Outcomes

  • Symptoms associated with BCRL (pain, heaviness, pressure and hardness) using modified visual analogue scale (VAS).(Four weeks during each treatment phase)
  • Goniometry of Upper Limb.(Four weeks during each treatment phase)

Investigators

Sponsor
Violeta Pajero Otero
Sponsor Class
Other
Responsible Party
Sponsor Investigator
Principal Investigator

Violeta Pajero Otero

Physiotherapist at the Mammary Pathology Unit

Hospital Universitario 12 de Octubre

Study Sites (1)

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