A Randomized , Parallel group , Open label , Active Controlled Clinical Study To Evaluate The Safety and Efficacy of a Topical Unani Formulation In the Management of Quba (Tinea corporis).

Dermatophytes are fungi responsible for tinea (ringworm) infections, affecting the hair, nails, and skin’s keratin layer. These infections are prevalent globally, particularly in tropical and subtropical regions, and are caused by fungi from three genera: Trichophyton, Microsporum, and Epidermophyton. Dermatophyte infections often result in annular skin lesions and can cause significant social, psychological, and economic issues in developing countries.

The treatment of dermatophyte infections can be challenging, especially with rising treatment failure rates. Common antifungal medications like chlorhexidine, itraconazole, and fluconazole can have severe side effects, particularly in pregnant women and children.

Traditional Unani medicine offers alternative treatments using formulations that contain ingredients like sulfur, copper sulfate, and borax, known for their anti-inflammatory, antiseptic, and blood-purifying properties. A clinical trial is underway to assess the safety and effectiveness of a topical Unani formulation for managing tinea corporis, as many of these treatments have yet to be scientifically evaluated.