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Tertiary Care With or Without Manual Therapy for Chronic Migraine

Not Applicable
Completed
Conditions
Chronic Migraine
Interventions
Other: Manual Therapy
Registration Number
NCT03395457
Lead Sponsor
Bournemouth University
Brief Summary

The aim of this study is to determine if adding manual therapy to care as usual reduces the discomfort from chronic migraine compared to care as usual alone

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
67
Inclusion Criteria

Female adults 18 years of age or older with a good command of English (to enable informed consent) Existing patients with chronic migraine as diagnosed by a clinical interview with a neurologist in line with the International Classification of Headache Diagnosis criteria (ICHD) Undergoing care as usual from the neurologist

Exclusion Criteria

Currently having or had manual therapy for neck, shoulder in the last six weeks.

Having a condition contraindicated for manual therapy including but not limited to inflammatory disorders, severe osteoporosis and tumours.

Identification of any medical 'red flags' by the neurologist including

  • Evidence of any central nervous system involvement for example:
  • Facial palsy (presence of ptosis/Horner's syndrome)
  • Visual disturbance (presence of blurred vision, diplopia, hemianopia)
  • Speech disturbance (presence of dysarthria, dysphonia, dysphasia such as expressive or receptive)
  • Balance disturbance (presence of dizziness, imbalance, unsteadiness, falls)
  • Paraesthesia (presence, location such as upper limb/lower limb, face)
  • Weakness (presence, location such as upper limb/lower limb)
  • Known major psychiatric or psychological conditions not under control

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Care as usualCare as usualThis is the care provided by the neurologist for chronic migraine.
Care as usual plus manual therapyCare as usualOther
Care as usual plus manual therapyManual TherapyOther
Primary Outcome Measures
NameTimeMethod
Change in migraine-related disability12 weeks

Headache Impact Test (HIT6). The six-item Headache Impact Test (HIT-6) provides a global measure of adverse headache impact and is used in screening and monitoring patients. The HIT-6 items measure the adverse impact of headache on social functioning, role functioning, vitality, cognitive functioning, psychological distress and the severity of headache pain.

The final HIT-6 score is obtained from simple summation of the six items and ranges between 36 and 78, with larger scores reflecting greater impact. The categories used for interpretation of impact are: little or no impact (49 or less), some impact (50-55), substantial impact (56-59), and severe impact (60-78).

Secondary Outcome Measures
NameTimeMethod
Change in Migraine Specific Quality of Life Questionnaire Score (MSQoL 2.1)12 weeks

The 14-item instrument measures how migraines affect daily functioning across three domains: Role function Restrictions (7 items assessing how migraines limit one's daily social and work-related activities); Role function prevention (4 items assessing how migraines prevent these activities); Emotional Functional (3 items assessing the emotions associated with migraines). It uses a 6-point scale: "none of the time," "a little bit of the time," "some of the time," "a good bit of the time," "most of the time," and "all of the time," which are assigned scores of 1 to 6, respectively. Scores are computed as a sum of item responses and rescaled from a 0 to 100 scale such that higher scores indicate better quality of life.

Headache Frequency12 weeks

Percentage of participants with reduction in headache frequency of greater than 50%

Trial Locations

Locations (1)

Salford Royal NHS Foundation Trust

🇬🇧

Manchester, United Kingdom

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