Genetic factors for the pathogenesis of kidney stones, nephrocalcinosis and related disturbances of urine compositio
Recruiting
- Conditions
- kidney stone suffer, nephrocalcinosisCalculus of kidneyN20.0
- Registration Number
- DRKS00013746
- Lead Sponsor
- niversitätsklinik Leipzig, Department für Innere Medizin, Neurologie und Dermatologie, Klinik für Endokrinologie und Neprhologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
Patients with renal stone disease, nephrocalcinosis and / or hypercalciuria.
Exclusion Criteria
Patients with known causative genetic or non-genetic causative disease.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Identification of a mutation in a known disease gene and correlation with the clinical phenotype.
- Secondary Outcome Measures
Name Time Method Identification of so far uncharacterized genes.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What genetic factors influence kidney stone formation in DRKS00013746 observational study?
How do mutations in SLC34A1 or CLDN14 contribute to nephrocalcinosis and urine composition changes?
Are there specific biomarkers for patient stratification in kidney stone and nephrocalcinosis research?
What are the molecular mechanisms linking hypercalciuria to nephrolithiasis in observational trials?
How does the GeFaSto study compare genetic risk factors for kidney stones with standard diagnostic criteria?