A Supervised Clinic-to-Community Exercise Intervention to Improve Cardiometabolic Health in Survivors of Adolescent and Young Adult Cancer: The ACSEND Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cardiometabolic Dysregulation
- Sponsor
- University of Southern California
- Primary Endpoint
- Cardiometabolic health - Insulin Resistance
- Status
- Withdrawn
- Last Updated
- 4 years ago
Overview
Brief Summary
The main goal of this clinical trial is to use a novel exercise intervention to improve cardiometabolic and biopsychosocial health outcomes in overweight/obese sedentary survivors of AYA cancers at risk for chronic comorbid conditions. The investigator's hypothesis is that an exercise intervention will improve: cardiometabolic health; body composition; physical fitness and biopsychosocial outcomes when compared to the attention control group.
Investigators
Christina Dieli-Conwright
Assistant Professor of Research
University of Southern California
Eligibility Criteria
Inclusion Criteria
- •AYA cancer survivors (18-39) Must be 12 months after treatment No metastatic disease
Exclusion Criteria
- •Metastatic disease Pregnancy
Outcomes
Primary Outcomes
Cardiometabolic health - Insulin Resistance
Time Frame: change from baseline to 4 months, to 8 months to 1 year
insulin resistance estimated by HOMA from a fasting blood sample
Cardiometabolic health - metabolic syndrome blood pressure
Time Frame: change from baseline to 4 months, to 8 months to 1 year
markers of metabolic syndrome, blood pressure via Omron cuff (mmHg)
Cardiometabolic health - metabolic syndrome waist circumference
Time Frame: change from baseline to 4 months, to 8 months to 1 year
markers of metabolic syndrome, waist circumference via measuring tape (cm)
Secondary Outcomes
- Muscular Strength (Physical Fitness)(change from baseline to 4 months, to 8 months to 1 year)
- Body Composition(change from baseline to 4 months, to 8 months to 1 year)
- Cardiorespiratory fitness (Physical Fitness)(change from baseline to 4 months, to 8 months to 1 year)