A Supervised Clinic-to-Community Exercise Intervention to Improve Cardiometabolic Health in Survivors of Adolescent and Young Adult Cancer: The ACSEND Trial
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 主要终点
- Cardiometabolic health - Insulin Resistance
研究概览
简要总结
The main goal of this clinical trial is to use a novel exercise intervention to improve cardiometabolic and biopsychosocial health outcomes in overweight/obese sedentary survivors of AYA cancers at risk for chronic comorbid conditions. The investigator's hypothesis is that an exercise intervention will improve: cardiometabolic health; body composition; physical fitness and biopsychosocial outcomes when compared to the attention control group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 39 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •AYA cancer survivors (18-39) Must be 12 months after treatment No metastatic disease
排除标准
- •Metastatic disease Pregnancy
结局指标
主要结局
Cardiometabolic health - Insulin Resistance
时间窗: change from baseline to 4 months, to 8 months to 1 year
insulin resistance estimated by HOMA from a fasting blood sample
Cardiometabolic health - metabolic syndrome blood pressure
时间窗: change from baseline to 4 months, to 8 months to 1 year
markers of metabolic syndrome, blood pressure via Omron cuff (mmHg)
Cardiometabolic health - metabolic syndrome waist circumference
时间窗: change from baseline to 4 months, to 8 months to 1 year
markers of metabolic syndrome, waist circumference via measuring tape (cm)
次要结局
- Muscular Strength (Physical Fitness)(change from baseline to 4 months, to 8 months to 1 year)
- Body Composition(change from baseline to 4 months, to 8 months to 1 year)
- Cardiorespiratory fitness (Physical Fitness)(change from baseline to 4 months, to 8 months to 1 year)
研究者
Christina Dieli-Conwright
Assistant Professor of Research
University of Southern California