Assessment of efficacy of anthelmintic drugs against soil-transmitted helminths in Thailand

Not Applicable

• Conditions: ascariasishookworm infectiontrichuriasisstrongyloidiasis; anthelmintics; albendazole; mebendazole; ivermectin; ascariasis; hookworm infection; trichuriasis; strongyloidiasis

• Registration Number: TCTR20190111001
• Lead Sponsor: Department of Parasitology, Faculty of Medicine, Chulalongkorn University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-11
• Study Completion: 2019-07-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 252

Inclusion Criteria

1) Age: 18-70 years old.
2) infected with any of the four species of STHs (i.e. Ascaris or hookworms or Trichuris or Strongyloides).

Exclusion Criteria

1) history of acute or severe chronic.
2) pregnancy or lactation
3) vomit within 4 hours after drug administration.
4) unable to provide a stool sample at follow-up.
5) known history of allergic reaction to ABZ, MBZ, IVR.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
cure rate 3 wks after treatment Modified Kato-Katz thick smear,Harada-mori culture

Secondary Outcome Measures

Name	Time	Method
egg reduction rate (ERR) 3 wks after treatment Modified Kato-Katz thick smear, Harada-mori culture