Is Harvesting the Peroneus Brevis an Alternative in Anatomic Ankle Ligament Reconstruction

Completed

• Conditions: Ankle Disease; Ankle (Ligaments); Instability (Old Injury)

• Registration Number: NCT06655350
• Lead Sponsor: Centre Hospitalier Universitaire de Saint Etienne

Brief Summary

Severe ankle sprains are the most frequent reason for emergency trauma consultations. Between 30% and 80% of sprains result in sequelae such as pain, joint derangement or instability. Ankle instability can itself lead to osteoarthritis if left untreated (1st cause of post-traumatic ankle osteoarthritis). To treat instability, ligament reconstruction is performed by harvesting the tendon of the gracilis muscle (inserted at knee level) to replace the damaged ankle ligaments. This tendon is also used for other ligament reconstructions (anterior cruciate ligament), so is not always harvested. Moreover, it represents an invasive procedure at a distance from the site of interest (the ankle), and can cause sensory nerve damage (20-60% of cases). For a long time, half of the peroneus brevis tendon was harvested as part of a now-defunct ankle stabilization technique (Hemi-Castaing). This tendon does, however, play a role in stabilizing the ankle.

Detailed Description

Before considering harvesting the peroneus brevis as an alternative to harvesting the gracilis, it is important to ensure that the peroneus brevis remains functional after harvesting. The aim of this study was to evaluate the potential for tendon regrowth after harvesting half of the peroneus brevis tendon after Hemi-Castaing-type ankle stabilization surgery.

Study Timeline

• Study Start: 2024-09-06
• Status Verified: 2024-10
• Primary Completion: 2024-10-11
• Study Completion: 2024-10-11
• Study First Submitted: 2024-10-22
• Study First Submitted QC: 2024-10-22
• Last Update Submitted: 2024-10-22
• Study First Posted: 2024-10-23
• Last Update Posted: 2024-10-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 19

Inclusion Criteria

• Adult one year after peroneus brevis harvesting (Hemi-Castaing)

Exclusion Criteria

• No.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Peroneus brevis diameter of a native ankle and at one-year postoperative harvested ankle.	Year : 1	Cross section area (mm²) at 40, 30, 20mm above the tip of the fibula, and 20mm from 5th metatarsal basis.

Secondary Outcome Measures

Name	Time	Method
Peroneus brevis MRI aspect of a native ankle and at one-year postoperative harvested ankle.	Year : 1	% T1 signal on the tendon at 40, 30, 20mm above the tip of the fibula, and 20mm from 5th metatarsal basis.

Trial Locations

Locations (1)

CHU de Saint-Etienne; 🇫🇷 Saint-Priest-en-Jarez, France