FACEFI : Cardiac Fatigue During Intense Exercises - Pilot Study

Not Applicable

• Conditions: Muscle; Fatigue, Heart
• Interventions: Procedure: Tests

• Registration Number: NCT02126891
• Lead Sponsor: Rennes University Hospital

Brief Summary

To attest if a cardiac fatigue appears (and to measure it if it does) during intense physical exercises in two groups of subjects:

* Canoeists from a training center of the French canoeing team during an intensive session of three weeks of endurance training;

* Young recruits in military school of officers in ground forces of the French army during an intensive.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-01
• Status Verified: 2014-04
• Study First Submitted: 2014-04-28
• Study First Submitted QC: 2014-04-29
• Study First Posted: 2014-04-30
• Last Update Submitted: 2015-01-23
• Last Update Posted: 2015-01-26
• Primary Completion: 2016-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: 23

Inclusion Criteria

• Healthy men between 18 and 35 years old;
• Giving their writing informed consent;
• And affiliated to the French social security.

Exclusion Criteria

• To be a smoker.
• To present any known pathology that forbids the realisation of any test, or that can alter the measurements: cardiovascular risk factors treated or not (diabetes, dyslipidaemia, arterial hypertension, obesity), cardiac arrhythmia, coronary disease, heart failure, cardiac pacemaker or defibrillator, valvular disease after surgery or not, kidneys failure with dialyse or not, kidney pulmonary cardiac or liver transplantation, chronic bronchopneumopathy, asthma, etc.
• To take any medication that could alter autonomic nervous system or cardiovascular adaptation to maximal exercise (anti-arrhythmia, anti-hypertensive, anti-inflammatory,...).
• Drinking exciting drinks (coffee or tee for example) in the 12h before the tests.
• To be under legal protection (trusteeship, guardianship) or to be deprived of liberty.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Military	Tests	10 young recruits in military school of officers in ground forces of the French army
Canoeists	Tests	13 canoeists from a training center of the French canoeing team

Primary Outcome Measures

Name	Time	Method
Measure of classical echocardiographic parameters to attest systolic and diastolic functions	day 8 (canoeists) / day 5 (military)	Speckle tracking will also be used to get strain parameters of the left ventricle. Measure will by recording daily before, during, and after a period of intensive training, in order to attest possible cardiovascular effects of such periods.; Echocardiographic data will be recorded at rest and during a submaximal exercise.

Secondary Outcome Measures

Name	Time	Method
Measure of classical heart rate variability parameters	day 8 (canoeists) / day 5 (military)	Measure will by recording daily before, during, and after a period of intensive training, in order to attest possible cardiovascular effects of such periods.; Measure will be recorded during 5 min resting and 5 min standing.

Trial Locations

Locations (1)

CHU Rennes; 🇫🇷 Rennes, France