FACEFI : Cardiac Fatigue During Intense Exercises - Pilot Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 23
- 试验地点
- 1
- 主要终点
- Measure of classical echocardiographic parameters to attest systolic and diastolic functions
研究概览
简要总结
To attest if a cardiac fatigue appears (and to measure it if it does) during intense physical exercises in two groups of subjects:
- Canoeists from a training center of the French canoeing team during an intensive session of three weeks of endurance training;
- Young recruits in military school of officers in ground forces of the French army during an intensive.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Healthy men between 18 and 35 years old;
- •Giving their writing informed consent;
- •And affiliated to the French social security.
排除标准
- •To be a smoker.
- •To present any known pathology that forbids the realisation of any test, or that can alter the measurements: cardiovascular risk factors treated or not (diabetes, dyslipidaemia, arterial hypertension, obesity), cardiac arrhythmia, coronary disease, heart failure, cardiac pacemaker or defibrillator, valvular disease after surgery or not, kidneys failure with dialyse or not, kidney pulmonary cardiac or liver transplantation, chronic bronchopneumopathy, asthma, etc.
- •To take any medication that could alter autonomic nervous system or cardiovascular adaptation to maximal exercise (anti-arrhythmia, anti-hypertensive, anti-inflammatory,...).
- •Drinking exciting drinks (coffee or tee for example) in the 12h before the tests.
- •To be under legal protection (trusteeship, guardianship) or to be deprived of liberty.
研究组 & 干预措施
Canoeists
13 canoeists from a training center of the French canoeing team
干预措施: Tests (Procedure)
Military
10 young recruits in military school of officers in ground forces of the French army
干预措施: Tests (Procedure)
结局指标
主要结局
Measure of classical echocardiographic parameters to attest systolic and diastolic functions
时间窗: day 8 (canoeists) / day 5 (military)
Speckle tracking will also be used to get strain parameters of the left ventricle. Measure will by recording daily before, during, and after a period of intensive training, in order to attest possible cardiovascular effects of such periods. Echocardiographic data will be recorded at rest and during a submaximal exercise.
次要结局
- Measure of classical heart rate variability parameters(day 8 (canoeists) / day 5 (military))