A Comparative Clinical study to evaluate the efficacy of Mashabaladi kwath Ghanavati with Kubja Prasarani tail in the management of Greeva Sandhigata Vata with reference to cervical spondylosis

Greeva sandhi gata vata is a degenerative type of pathological conditions in the body can be considered under the broad umbrella “Vata vyadhi”. Sandhi gata vata is mentioned under Vata vyadhi. Greeva sandhi gata Vata is a Vata-dominant condition that affects the cervical region (neck area). Though it is not directly mentioned in the Brihatrayi, Ayurvedic references allow us to treat it as an individual Pathology. When aggravated Vata Dosha accumulates in the Greeva Asthi Sandhi (cervical joint) which leads to Greeva sandhi gata vata, leading to symptoms of sandhi gata Vata. In Vata Vyadhi chikitsa , Acharya Charak mentions sandhi gata Vata. The symptoms of sandhi gata Vata, as outlined in Ayurvedic classics, includes    Shoola (pain),   Prasarna Achunchan Savedana (pain full flexion and extension), Shotha (swelling),Vatapurnadritisparsha (sensation of fullness and heaviness) ,Hanti Sandhi gatah (impairment or difficulty in joint function).Cervical spondylosis is the most prevalent degenerative condition of the cervical spine, predominantly affects individuals aged 40 and older. Progressive degenerative changes, including intervertebral disc desiccation, degeneration of uncovertebral and facet joints. Osteophyte formation frequently accompanies these changes, potentially causing axial neck pain, neck stiffness, Restricated movement of neck significantly impairing daily function and quality of life. Given its prevalence and associated disability, cervical spondylosis imposes a substantial economic burden, necessitating timely recognition and evidence-based management to mitigate this condition’s impact on patient`s lives.

The prevalence of cervical spondylosis was 13.76%, although it differed significantly among the urban, suburban, and rural populations (13.07%, 15.97%, and 12.25%, respectively). Moreover, it was higher in females than in males (16.51% vs 10.49%). The highest prevalence was in the age group from 45 to 60 years old. There were positive associations between engaging in mental stress, prolonged computer use, overexertion and repeated spinal strain from travels or sports, high housework intensity and sleep duration of less than 7 h/day with cervical spondylosis.

NEED OF STUDY**:****-**1.The prevalence of cervical Spondylosis in India varies with studies reporting figures ranging from 13.76-28.6%, mainly 13.76% with Variation across urban, suburban and rural populations.

2.Greeva Sandhigata vata is the most common degenerative disorder that affects the movements of the upper limbs particularly in most productive period of time.

3. Even though a lot of medications were invented in these contemporary medical sciences that there are no satisfactory treatments for degenerative joint disorders.

4.By taking into consideration, the prevalence rate of cervical spondylosis and overcoming the above expensive therapeutics, there is a great need to find out effective management of Greeva sandhi gata vata in ayurvedic.

5.The ayurvedic medicines available for Greeva Sandi gata vata was statistically significant improvement in some parameters in Greeva sandhi gata vata. But they are does not have much more effect on the specific symptoms as Neck pain, Neck stiffness, Restricated movement of neck, Pnumbness, Headache.

6. So, going to use Masha Baladi kwatha Ghanavati described by Acharya Chakradatta and Kubja Prasarani tail also described by Acharya Chakradatta in the form Greeva Basti. They can be producing beneficial and positive effects in Greeva sandhi gata vata That’s why selected this topic and presented it.

**BASIS OF DRUG SELECTION -**In Ayurveda for the management of Greeva sandhi gata vata; the concept ofsamprapti Vighatana is useful and is done by the use of Deepan and Pachan medicines which will be beneficial to reduce the formation of Aama dosha. Analysis of samprapti Vighatana Chikitsa of Greevasandhi Vata (Cervical Spondylosis) by Mashabaladi Kwatha Ghatavati ingredients such as eranda , bala, Masha and Kapikacchu will work together to pacify Vata and kapha doshas with properties, like Ushna Virya (hot potency) and Guru Snigdha (heavy and unctuous properties), and Eranda, Masha, Rasna & Hingu having anti-inflammatory, antioxidant and analgesic properties. Bala having nourishing and strengthening properties (Balya). Kapikacchu and Ashwagandha has rejuvenating and nervine-tonic properties and Rasayana .Kubja prasarani taila has ingredients like Prasarani, Pippali, Shatpushpa, Chitraka, Devadaru, Rasna, Jatamansi, Bala, and Saindhava Lavana, which will work together to pacify Vata dosha with properties like Katu, Tikta Rasa and Ushn virya (hot potency), and will contribute to their therapeutic effect as specific vatahar. Prasarani, Pippali, Devadaru, Rasna & Chitraka as vata pacification, pain relief (Shoolahara), inflammation reduction (Shothahara), analgesic, antioxidant, and digestive (eepana Pachana). The Rasayana properties of the ingredients promote overall rejuvenation and well-being.

This is randomized doubled armed open level clinical study. A  total 40 patients will be enrolled and located  into two groups on the basis of assessment criteria (subjective criteria) of Greeva sandhi gata vata (Cervical Spondylosis)with 15 patients each.  In Group -A 20 patients will take 500mg of Mashabaladi kwath Ghanavati twice in a day with Luke warm water& Group-B  20 patients will take 500mg of Mashabaladi kwatha Ghanavati twice in a day with Luke warm water with Greeva basti of kubaj prasarani tail. To Compare the efficacy of Mashabaladi kwath Ghanavati with Greeva Basti of kubja prasarani tail in management Greeva sandhi gata vata disease (cervical spondylosis).To Compare the efficacy of Mashabaladi kwath Ghanavati with Greeva Basti of kubja prasarani tail in management Greeva sandhi gata vata disease (cervical spondylosis).To study aims to evaluate and compare the  clinical efficacy of Mashabaladi Kwath Ghanavati with Greeva basti of Kubja prasarani Tail in the management of Greeva sandhi gata vata ( cervical spondylosis)