Therapeutic Exercises for Pain and Disability in Knee Osteoarthritis

Not Applicable

Not yet recruiting

• Conditions: Knee Osteoarthritis

• Registration Number: NCT07128875
• Lead Sponsor: Riphah International University

Brief Summary

This study aims to evaluate the effectiveness of structured therapeutic exercises in reducing pain and disability among older adults diagnosed with knee osteoarthritis. The intervention will involve a supervised physical therapy program targeting muscle strength, joint mobility, and functional capacity. Participants will undergo 6 weeks of therapy, and improvements in pain and physical function will be measured using validated scales.

Detailed Description

Knee osteoarthritis (OA) is a leading cause of chronic pain and mobility limitations in the elderly population. Therapeutic exercises play a significant role in managing OA symptoms by strengthening the quadriceps, improving joint flexibility, and reducing stiffness. This study will enroll 60 participants aged 50-75 years diagnosed with knee OA. They will undergo a combination of strengthening, range of motion (ROM), and stretching exercises tailored to their condition. The intervention also includes adjunctive modalities such as hot pack and TENS to reduce pain and facilitate muscle engagement. Outcome measures will assess pain intensity, functional ability, and lower limb endurance before and after the intervention.

Study Timeline

• Study First Submitted: 2025-07-14
• Status Verified: 2025-08
• Study Start: 2025-08-17
• Study First Submitted QC: 2025-08-18
• Last Update Submitted: 2025-08-18
• Study First Posted: 2025-08-19
• Last Update Posted: 2025-08-19
• Primary Completion: 2026-07-17
• Study Completion: 2026-07-17

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 56

Inclusion Criteria

Minimum Age: 50 Years Maximum Age: 75 Years Sex: All Accepts Healthy Volunteers: No

Inclusion Criteria:

• Diagnosed with knee OA
• Aged 50-75 years
• Experiencing pain or functional limitation
• Able to attend supervised sessions
• Provided informed consent

Exclusion Criteria

• History of total knee replacement

• Severe cardiovascular or neurological conditions
• Acute injury or fracture in lower limb
• Uncontrolled hypertension or diabetes

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Pain Intensity	6 Months	Pain intensity will be assessed using the Visual Analog Scale (VAS), which ranges from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores represent worse outcomes.

Secondary Outcome Measures

Name	Time	Method
Change in Physical Disability	6months	Physical disability will be measured using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). The WOMAC consists of 24 items scored from 0 (none) to 4 (extreme), yielding a total score range from 0 to 96, where higher scores indicate worse disability

Trial Locations

Locations (1)

Riphah international University Malakand Campus; 🇵🇰 Malakand, Kpk, Pakistan