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Impact of letrozol on oocyte quality and IVF success

Not Applicable
Recruiting
Conditions
Condition 1: Infertility. Condition 2: Infertility. Condition 3: Infertility. Condition 4: Infertility. Condition 5: Infertility. Condition 6: Infertility.
Female infertility associated with anovulation
Female infertility of tubal origin
Female infertility of uterine origin
Female infertility of other origin
Female infertility, unspecified
Encounter for male factor infertility in female patient
N97.0
N97.1
N97.2
Registration Number
IRCT20200328046881N1
Lead Sponsor
Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Female
Target Recruitment
220
Inclusion Criteria

Infertile patient that IVF candidate with 40 years old or less
use of antagonist protocol for IVF

Exclusion Criteria

Patient with cancer
Use of IVF protocol except antagonist protocol

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
umber of metaphase 2 oocyte. Timepoint: After ovum pick up. Method of measurement: Number of metaphase 2 by counting metaphase 2 oocyte by embryologist.
Secondary Outcome Measures
NameTimeMethod
Oocyte quality. Timepoint: After ovum pick up. Method of measurement: Based on morphology of different parts of metaphase 2 oocyte which determined by embryologist.;Oocyte maturation rate. Timepoint: After ovum pickup. Method of measurement: Number of metaphase2 oocytes divided to number of picked up oocytes.;Fertilization rate. Timepoint: After injection of sperm to metaphase 2 oocyte. Method of measurement: Number of 2PN divided to number of metaphase 2 oocyte that injected.;Clinical pregnancy rate. Timepoint: After embryo transfer. Method of measurement: Number of pregnancy that confirmed with presence of gestational sac in ultrasonography divided to number of fresh or frozen embryo transfer cycles.
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