Haemochromatosis and neuromuscular complaints - A prospective clinical study

Completed

• Conditions: haemochromatosis; iron storage disorder; 10027424; 10029317

• Registration Number: NL-OMON30114
• Lead Sponsor: Atrium Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

- age 18 years or older
- definite diagnosis of haemochromatosis: i.e., (a) Transferrin saturation in fasting state > 45 % AND (b) Homozygosity for C282Y or compound heterozygosity C282Y/H63D
- informed written consent before entering the study

Exclusion Criteria

- unable to read and understand the questionnaires (in Dutch)
- unable to follow-up

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Evidence of a neuromuscular disorder (e.g., neuropathy or myopathy). Cause of<br /><br>this neuromuscular disorder. Prevalance of neuromuscular symptoms and signs.<br /><br>The impact of neuromuscular symptoms and signs on the quality of life. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>na</p><br>