Hemodynamic Effects of Dry Sauna Followed by Cold Water Immersion in Healthy Subjects

Not Applicable

Completed

• Conditions: Arrhythmias; Blood Pressure
• Interventions: Other: Sauna and cold water bath

• Registration Number: NCT02598258
• Lead Sponsor: Montreal Heart Institute

Brief Summary

The purpose of this study is to determine the safety on sauna followed by cold water bath, a common practice in many countries, 30 healthy subjects aged 40 years and older will be at the Montreal Heart Institute Prevention and Cardiac Rehabilitation centre.

Detailed Description

To determine the safety on sauna followed by cold water bath, a common practice in many countries, 30 healthy subjects aged 40 years and older will be at the Montreal Heart Institute Prevention and Cardiac Rehabilitation centre. A recent complete evaluation will have excluded any cardiac condition. Subjects will first spend 10 minutes in a dry sauna at 85 degrees celtius. Immediately after , subjects will be immersed in a cold water bath (ICool , Australia) at a temperature of 5 degrees celtius for approximately one minute. Blood pressure , ecg , gaz exchange and thoracic impedance will be measured during sauna and cold water bath.

Principal goal of study: to determine the safety of this practice. Secondary goals of study: to measure the blood pressure response, heart rate, presence of arrythmyas, cardiac output and cerebral perfusion during both conditions.

Primary endpoint: Change in systolic blood pressure from sauna (after 10 minutes ) to cold water (after one minute).

Physiologic measurements: continuous ECG monitoring, BP measurements at every 3 minutes during sauna and at one minute in the cold bath, gaz exchange with a portable equipment (Cosmed K4), bioimpedance and cerebral perfusion with a single frontal NIRS electrode.

Study Timeline

• Study Start: 2015-10
• Study First Submitted: 2015-10-08
• Study First Submitted QC: 2015-11-04
• Study First Posted: 2015-11-05
• Primary Completion: 2018-12
• Study Completion: 2021-12-30
• Status Verified: 2022-08
• Last Update Submitted: 2022-08-22
• Last Update Posted: 2022-08-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

• Healthy women and men aged 40 and older with a recent complete medical evaluation including a normal resting ECG and a normal symptom-limited treadmill exercise test.

Exclusion Criteria

• Any cardiac condition, abnormal exercise test, hypertension, type I diabetes and presence of any medications that may affect blood pressure.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Sauna + Cold Water Bath	Sauna and cold water bath	Subjects will first spend 10 minutes in a dry sauna at 85 degrees celtius. Immediately after , subjects will be immersed in a cold water bath (ICool , Australia) at a temperature of 5 degrees celtius for approximately one minute. Blood pressure , ecg , gaz exchange and thoracic impedance will be measured during sauna and cold water bath.

Primary Outcome Measures

Name	Time	Method
Blood pressure	Difference between baseline and 11 minutes of intervention.

Secondary Outcome Measures

Name	Time	Method
Arrhytmias	Number of arrhytmias during all 25 minutes of the intervention.	Patients will use a HOLTER during all experiment. Total time: 25 minutes.
Blood pressure	Measured at 10 minutes after the end of the intervention (recovery period).

Trial Locations

Locations (1)

Cardiovascular Prevention and Rehabilitation Center; 🇨🇦 Montreal, Quebec, Canada