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Clinical Trials/CTRI/2025/12/098250
CTRI/2025/12/098250
Not yet recruiting
Phase 2/3

A Comparative Evaluation Of Ultrasound Guided Costoclavicular Brachial Plexus Block Versus Axillary Brachial Plexus Block For Upper Limb Surgery - A Prospective Randomised Clinical Study.

Department Of Anaesthesiology And Critical Care1 site in 1 country60 target enrollmentStarted: December 10, 2025Last updated:

Overview

Phase
Phase 2/3
Status
Not yet recruiting
Sponsor
Department Of Anaesthesiology And Critical Care
Enrollment
60
Locations
1
Primary Endpoint
To Compare The Efficacy Of Duration Of Analgesia In Costoclavicular Brachial Plexus Block Versus Axillary Brachial Plexus Block.

Overview

Brief Summary

1. To compare costoclavicular vs axillary brachial plexus block for the onset of effective sensory and motor blockade.

 

2. To compare costoclavicular vs axillary brachial plexus block for the demand of additional analgesics/sedatives (time for first analgesic/sedative demand and total 24-hour analgesic requirement) if needed.

 

3. To compare costoclavicular vs axillary brachial plexus block in terms of intensity of pain, if experienced by the patient using NRS (Numerical Rating Scale)

 

4. To compare the incidence of complications – Dyspnea, Horner syndrome, hemi-diaphragmatic paralysis (after 30 min and in post anesthesia care unit), local anesthesia toxicity, pneumothorax incidence.

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
Participant Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • ASA Grade 1 and 2 BMI 18.5 to 24.9.

Exclusion Criteria

  • ASA Grade 3 and 4 Coagulation Abnormalities Infections at site Liver/ Renal/ Heart diseases Pregnancy Neurological deficit.

Outcomes

Primary Outcomes

To Compare The Efficacy Of Duration Of Analgesia In Costoclavicular Brachial Plexus Block Versus Axillary Brachial Plexus Block.

Time Frame: From the onset until the effect wears off.

Secondary Outcomes

  • To compare the onset time of effective sensory & motor blockade in costoclavicular versus axillary brachial plexus block.(Time taken from giving the block, with assessments every 5 minutes, until adequate sensory & motor blockade occurs.)
  • To compare costoclavicular versus axillary brachial plexus block in terms of intensity of pain, if experienced by the patient using numerical rating scale.(Pain assessment using numerical rating scale every 5 minutes until surgical readiness, then every 30 minutes during intraoperative period, & then every 1 hour in the postoperative period.)
  • To compare costoclavicular versus axillary brachial plexus block for the demand of additional analgesia/sedatives if needed.(Time taken for first analgesic/sedative demand & total 24-hour analgesic requirement if needed.)
  • To compare the incidence of complications in costoclavicular versus axillary brachial plexus block.(Assessment of patient every 30 minutes intraoperatively & every 1 hour in the post-anaesthesia care unit for dyspnea, Horner’s syndrome, hemidiaphragmatic paralysis, local anaesthetic toxicity, & pneumothorax.)

Investigators

Sponsor
Department Of Anaesthesiology And Critical Care
Sponsor Class
Government medical college
Responsible Party
Principal Investigator
Principal Investigator

DR Mohd Asim

Jawaharlal Nehru Medical College, Aligarh Muslim University.

Study Sites (1)

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