A clinical study to find whether dexmedetomidine provides adequate comfort to patients during awake nasal fibreoptic intubatio
Phase 4
- Conditions
- Health Condition 1: null- Patients who are scheduled to undergo surgery and require awake nasal fibreoptic intubation in view of anticipated difficult oral intubation
- Registration Number
- CTRI/2010/091/003044
- Lead Sponsor
- Anitha Shenoy
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
Inclusion criteria : Patients of either gender aged above 18 years requiring awake nasal fibreoptic intubation
Exclusion Criteria
Exclusion Criteria:
Patients with ASA physical status IV, raised intracranial pressure, uncontrolled seizure disorder / known psychiatric illness, receiving α2 agonists/antagonists in the past two weeks, where either dexmedetomidine or benzodiazepine administration is contra-indicated and patients with acute unstable angina, laboratory confirmed acute myocardial infarction within the past 6 weeks, heart rate <50bpm, systolic blood pressure <90 mmHg, or complete heart block unless they have a pacemaker, patients with elevated liver enzymes > 2 times normal
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fibrescopy score<br>Intubation score<br>Post intubation scoreTimepoint: At end of visualisation of glottis<br>At point of intubation<br>At end of intubation
- Secondary Outcome Measures
Name Time Method Time for endoscopy and time for intubation<br>Ease of endoscopy and intubation<br>Number of attempts taken at endoscopy and intubation<br>Postoperative patient satisfaction score<br>Timepoint: At end of intubation process and 24 h after the surgical procedure