Prevention of recurrent urinary tract infections by intravesical administration of hyaluronic acid and chondroiti
Completed
- Conditions
- Urological and Genital Diseasesrinary tract infections (UTIs)Other disorders of urinary system
- Registration Number
- ISRCTN76354426
- Lead Sponsor
- Magna Graecia University (Italy)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
1. Women aged 18 - 80 years old
2. Spontaneous urination
3. Greater than three uncomplicated UTIs/previous year
4. Free from UTIs at the beginning of study
5. No ongoing prophylactic antibiotic treatment
6. Able to provide informed consent
Exclusion Criteria
1. Greater than 50 ml residual urine
2. Neurological bladder disease
3. Known neoplasia, urinary stone or urinary tract abnormality
4. Use of indwelling catheter
5. Renal insufficiency
6. Diabetes
7. Current corticosteroid use
8. Pregnancy
9. Immunosuppressive disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rate of UTIs per patient per year. Outcome assessment at 1, 3, 6, 9 and 12 months.
- Secondary Outcome Measures
Name Time Method Outcome assessment at 1, 3, 6, 9 and 12 months:<br>1. Time to UTI recurrence<br>2. Rate of adverse events