Study to Compare Standard Perimetry With the New Scotoma-Oriented Perimetry (SCOPE) Using a New Fast German Adaptive Threshold Estimation (GATE) in Glaucoma Patients

• Conditions: Primary Open Angle Glaucoma (POAG)
• Interventions: Device: Perimetry; Device: Confocal Scanning Laser Tomography; Device: Optical Coherence Tomography (OCT)

• Registration Number: NCT00902109
• Lead Sponsor: University Hospital Tuebingen

Brief Summary

The purpose of this study is to compare the two psychophysical perimetric techniques regarding progression of the visual field.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2009-05-12
• Study First Submitted QC: 2009-05-12
• Study First Posted: 2009-05-14
• Study Start: 2010-04
• Status Verified: 2016-01
• Last Update Submitted: 2016-01-31
• Last Update Posted: 2016-02-02
• Primary Completion: 2016-12
• Study Completion: 2016-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• primary open angle glaucoma (POAG)
• spherical ametropia max. ± 8 dpt
• cylindrical ametropia max. ± 3 dpt
• distant visual acuity > 10/20
• pupil diameter > 3 mm

Exclusion Criteria

• diabetic retinopathy
• asthma
• history of epilepsy or significant psychiatric disease
• medications known to effect visual field sensitivity
• infections (e.g., keratitis, conjunctivitis, uveitis)
• severe dry eyes
• miotic drug
• squint
• nystagmus
• albinism
• any ocular pathology, in either eye, that may interfere with the ability to obtain visual fields
• keratoconus
• intraocular surgery (except for uncomplicated cataract surgery) performed < 3 month prior to screening
• history or signs of any visual pathway affection other than glaucoma
• history or presence of macular disease and/or macular edema, ocular trauma, medications known to affect visual field sensitivity

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
perimetry, HRT, OCT	Perimetry	perimetry, HRT, OCT
perimetry, HRT, OCT	Confocal Scanning Laser Tomography	perimetry, HRT, OCT
perimetry, HRT, OCT	Optical Coherence Tomography (OCT)	perimetry, HRT, OCT

Primary Outcome Measures

Name	Time	Method
Comparison of rate of progression	36 month	Perimetric measures every 3 month over 3 years

Trial Locations

Locations (1)

Institute for Ophthalmic Research; 🇩🇪 Tuebingen, Germany