A Single-center Observational Study to Find Biomarkers for the Outcome of Catheter Ablation in Patients With Atrial Fibrillation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Number of patients with short term reoccurrences of atrial fibrillation after ablation.
研究概览
简要总结
The investigators aim to find biomarkers to determine the success of pulmonary vein isolation for the treatment of atrial fibrillation.
详细描述
The investigators perform an observational study in patients undergoing pulmonary vein ablation to treat atrial fibrillation. Additionally, electrophysiological procedures not related to pulmonary vein isolation are also followed. The aim of the study is finding biomarkers that are able to predict short-term outcome of the procedure.The primary endpoint is defined as reoccurrences of atrial fibrillation within the first three months after pulmonary vein isolation.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with atrial fibrillation scheduled for pulmonary vein isolation with either radiofrequency of cryoballoon
- •patients scheduled for an electrophysiological study without ablation
- •patients with a catheter ablation at the cavotricuspid isthmus for the treatment of right atrial flutter
排除标准
- •patients with concurrent pulmonary vein isolation and ablation of the cavotricuspid isthmus
- •Acute myocardial infarction, coronary artery bypass graft surgery or open heart surgery within less than 3 months prior to inclusion
结局指标
主要结局
Number of patients with short term reoccurrences of atrial fibrillation after ablation.
时间窗: 3 months
Holter ECGs and ECGs after atrial fibrillation ablation
次要结局
- Change in heart rate after pulmonary vein isolation(3 days.)
研究者
Prof. Dr. Christian Meyer
Prof. Dr. Christian Meyer
Universitätsklinikum Hamburg-Eppendorf