Objective: To compare the clinical outcomes of ultrasound guided percutaneous nephrolithotomy ( US PCNL) and anatrophic nephrolithotomy (ANL) in the treatment of staghorn renal stones.Methods: Historical cohort study.Between October 2016 and July 2

Regarding the primary outcome, the stone-free rate was significantly lower in the US-PCNL group , whereas the stone clearance rate was not significantly different . The major and minor complications between the two groups were not significantly different; however, the US-PCNL group had a significantly lower transfusion rate than the ANL group . The total operative time in both groups was not different; however, the length of stay at hospital for the US-PCNL was significantly shorter than for the ANL group .