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Exercise-snacks at Work: Impact on Cardiometabolic Parameters

Not Applicable
Terminated
Conditions
Sedentary Time
Overweight and Obesity
Work-Related Condition
Interventions
Other: Exercise-snacks program
Registration Number
NCT05942144
Lead Sponsor
University of Avignon
Brief Summary

The main objective is to measure the effects of intense brief exercise program in the workplace of administrative staff on the cardio-metabolic health

Detailed Description

Backgrounds: Very short (\< 1 minute) and intense exercises, entitled "exercise-snacks", have been reported to be effective 1) in improving physical fitness over 6 weeks and 2) in improving vascular function and lowering blood glucose levels over one day. These studies were all carried out in the laboratory. The question therefore arises as to whether these acute vascular and metabolic benefits, as well as those on physical fitness, are sustainable over time following a chronic "exercise-snacks" program applicable in the professional environment to sedentary, overweight people.

Aims of this project is therefore to measure the effects of an "exercise-snacks" type physical activity program in the workplace of administrative staff on the cardio-metabolic health and sedentary behaviour of staff.

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
23
Inclusion Criteria
  • administrative staff,
  • age between 30 and 60,
  • body mass index ≥25kg/m²,
  • sedentary time ≥7h/day,
  • minimum 3 working days on site,
  • no known cardiovascular or metabolic pathology, social security affiliation or benefit,
  • ability and willingness to give free, written and informed consent.
Exclusion Criteria
  • pregnant or breast-feeding women,
  • anti-hypertensive treatment, beta-blockers and anti-diabetics,
  • known contraindications to physical activity (articular, cardiac or other),
  • exercise-induced asthma,
  • lack of motivation of subjects posing problems of compliance and adherence to the exercise program,
  • participation in a study in the preceding 3 months, ongoing participation in a clinical trial.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Exercise-snacks groupExercise-snacks programThey will perform a "exercise-snacks" program and receive information about physical activity
Primary Outcome Measures
NameTimeMethod
Changes in aerobic fitnessat inclusion, at the end of the 4-weeks program and 1 month following the end of the program

Aerobic fitness will be assessed via the Chester step test's prediction of VO2max

Secondary Outcome Measures
NameTimeMethod
Changes in carotid-femoral pulse wave velocityat inclusion, at the end of the 4-weeks program

by Sphygmocor, in m.s-1

Changes in blood pressureat inclusion, at the end of the 4-weeks program and 1 month following the end of the program

systolic, diastolic, mean and pulsed

Intensity of exercise-snacksduring the 4-weeks program

Heart rate during exercise-snacks in % heart rate max

Changes in peak shear rate of superficial femoral arteryat inclusion, at the end of the 4-weeks program

measured by echocardiography (Vivid Q, GE) during hyperemia, in s-1

Changes in mean amplitude of glycemic excursionsone week before the beginning of the program and the first week of the program and the 2 lastest weeks of the program

measured by continuous glucose monitoring (FreeStyle), in mmol.L-1

Changes in heart ratebetween the beginning and end of the 4-week exercise program and 4 weeks after the program.

Heart rate at rest, at the end of the Chester step test and during exercise

Adherence of staff in the experimental group by analyzing accelerometric data.during the 4-weeks program

Total number of exercise-snacks performed during the 4-week program by analysing accelerometers data

Changes in carotid complianceat inclusion, at the end of the 4-weeks program

by echocardiography (Vivid Q) in mm2 mmHg-1

Changes in lean massbetween the start and end of the 4-week exercise program and 4 weeks after the program

measured by InBody, in kg

Change in physical activity behaviour at work of staffbetween the start and end of the 4-week exercise program.

Theory of planned behavior questionnaire, score range from 20 to 80 with higher scores mean a better outcome.

Changes in flow mediated dilation of superficial femoral arteryat inclusion, at the end of the 4-weeks program

measured by echocardiography (Vivid Q, GE) , in %

Changes in nitrate mediated dilation of superficial femoral arteryat inclusion, at the end of the 4-weeks program

by echocardiography (Vivid Q, GE), in %

Changes in superficial femoral artery complianceat inclusion, at the end of the 4-weeks program

by echocardiography (Vivid Q, GE), in mm2 mmHg-1

Changes in post-occlusive skin perfusionat inclusion, at the end of the 4-weeks program

by Laser Doppler (Perimed), in perfusion unit, in area under the curve, in time to peak

Changes in level of habitual physical activitybetween the start and end of the 4-week exercise program and 4 weeks after the program

Physical Activity questionnaire

Changes in rating of perceived exertionbetween the start and end of the 4-week exercise program and 4 weeks after the program

measured during the Chester test, score range from 7 to 20 with higher scores mean a worse outcome.

Changes in carotid intima-thicknessat inclusion, at the end of the 4-weeks program

by echocardiography (Vivid Q) in mm

Changes in fat massbetween the start and end of the 4-week exercise program and 4 weeks after the program

measured by InBody, in kg

Trial Locations

Locations (1)

Avignon University

🇫🇷

Avignon, France

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