NCT07067541已完成不适用
Clinical Observation of Topical Lidocaine Cream Combined With Moisturizing Cream in the Treatment of Atopic Dermatitis
First Affiliated Hospital of Kunming Medical University1 个研究点 分布在 1 个国家目标入组 25 人开始时间: 2023年10月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- change in SCORAD (SCORing Atopic Dermatitis) from baseline
研究概览
简要总结
Twenty-five patients with atopic dermatitis applied lidocaine cream plus a moisturizer to the right limb and lidocaine cream alone to the left limb, twice daily for four weeks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male or female patients aged 18-65 years.
- •Clinical diagnosis of atopic dermatitis according to the 2020 Guidelines for the Diagnosis and Treatment of Atopic Dermatitis in China (symmetrical eczematous lesions for ≥6 months plus personal/family atopy history or elevated IgE/eosinophilia).
- •Voluntarily signed informed consent form.
排除标准
- •Active heart, liver, kidney, or other serious systemic illness.
- •History of viral or bacterial infection within 1 month prior to enrollment.
- •Immunocompromised patients or those receiving systemic immunosuppressive therapy.
- •Known allergy to lidocaine, moisturizer components, or any study-related topical agents.
- •Pregnant or breastfeeding women.
- •Use of topical corticosteroids or calcineurin inhibitors within 2 weeks prior to enrollment.
研究组 & 干预措施
Control Group
Active Comparator
干预措施: Control lidocaine cream (Drug)
Experimental group
Experimental
干预措施: Experimental lidocaine cream + moisturizer cream (Drug)
结局指标
主要结局
change in SCORAD (SCORing Atopic Dermatitis) from baseline
时间窗: 4 weeks
For each patient, a score will be obtained at baseline, after 4 weeks. The minimum score is 0 (best outcome) and the maximum score is 103 (worst outcome).
次要结局
未报告次要终点
研究者
Tang Junting
Director
First Affiliated Hospital of Kunming Medical University
研究点 (1)
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