Using Behavioral Economics to Achieve Improved Healthy Behavior Outcomes in Breast Cancer Survivors
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 310
- 试验地点
- 2
- 主要终点
- Urinary levels of 8-OHdG
研究概览
简要总结
Preventing or reducing obesity is one factor that has been hailed as a way to improve quality of life, reduce recurrence, and increase survival rates among breast cancer survivors. An experienced team of multi-disciplinary researchers has developed an innovative and unique approach to encourage enhanced nutrition and exercise behaviors in this population using principles of behavioral economics. In particular, the use of social norms or exemplars has been shown in other applications to be effective, and if successful in this population could be inexpensively scaled up for widespread adoption. The proposed pilot study develops a system of text messages for social/mobile media that will provide ongoing reinforcement of desired behavior in breast cancer survivors. These messages would focus on achieving compliance with the expert-developed nutrition and exercise recommendations of the American Cancer Society. In the main study, 310 breast cancer survivors will be randomly placed in intervention and control groups for the 12 week study. Behavior change will be measured using established measures of self-reported behavior. In a sub-study, 60 of the breast cancer survivor participants will also provide blood and urine samples so changes in biomarkers can be assessed. The impact of the study will be measured by biomarkers and self-reported survey responses.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 75 Years(Adult, Older Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Age: 20-75 years old
- •No current pregnancy or lactation
- •Was diagnosed with Stage 0-IIIB disease and completed all local and systemic therapy (including Herceptin) at least 3 months prior to entry. Women can be on or off anti-hormone therapy.
- •Ambulatory
- •Willing to be randomized
排除标准
- •Current participation in other treatment (chemo/radiotherapy) clinical trials
- •Instructed by doctor not to exercise
- •Cannot read English
- •Not able to receive text messages
结局指标
主要结局
Urinary levels of 8-OHdG
时间窗: 3 months
To measure oxidative stress DNA damage. ug/mmol creatinine
次要结局
- physical activity(3 months)
- Serum total antioxidant capacity(3 months)
- Intake of fruit and vegetable behavior(3 months)
- Self-efficacy(3 months)
