Microbiota and Carcinogenesis of Small-intestine Neuroendocrine Tumors
Recruiting
- Conditions
- Small-intestine Neuroendocrine Tumors
- Interventions
- Other: Blood and stool sampling
- Registration Number
- NCT06624865
- Lead Sponsor
- Hospices Civils de Lyon
- Brief Summary
The aim of the study is to investigate the impact of the microenvironment on tumorigenesis of small intestinal neuroendocrine tumors often located in the terminal ileum, without identified driver mutations.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 75
Inclusion Criteria
- Patient with one or more small-intestine neuroendocrine tumor with indication of surgery
- Patient with consent for the collection, storage and reuse of data associated with his/her disease
- Age ≥ 18 years at the time of inclusion
- Non-objection statement obtained for participation in the study
Exclusion Criteria
- Patients with poorly differentiated neuroendocrine carcinoma or NET (neuroendocrine tumors) of non-intestinal origin or mixed tumors (MiNEN)
- Pregnant, parturient or breast-feeding women
- Minors
- Persons deprived of liberty by judicial or administrative decision
- Adults under legal protection (guardianship, curatorship)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description patient with indication for small-intestine neuroendocrine tumor surgery Blood and stool sampling The target population for this study is consecutive patients with small-intestine neuroendocrine tumor for whom surgery is indicated
- Primary Outcome Measures
Name Time Method Composition of microbiota At day 1 and month 3 Determination of the composition of blood, fecal, intra- and peri-tumoral microbiota in patients undergoing surgery for small-intestine neuroendocrine tumor.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Edouard Herriot University Hospital
🇫🇷Lyon, France